is a genus of eucoccidian parasites, which globally infects humans and various animals. In addition to economic losses in livestock industries, the parasite is a zoonosis that infects humans through contaminated beef and pork with the parasite sarcocysts. Therefore, this study was carried out to assess contamination in beef and industrial raw beef burger samples from butcheries and retail stores in Tehran, Iran.
View Article and Find Full Text PDFBackground: Toxoplasmosis, a protozoan parasitic disease caused by , has been a serious human and veterinary medicine problem with global distribution. In the current study, we assessed immunogenicity and protective efficiency of a novel dual-promoter DNA vaccine, harboring SAG1 and GRA7 genes, from RH strain of () with or without CpG-ODN as adjuvant in a murine model.
Methods: BALB/c mice were immunized intramuscularly with pVitro-SAG1-GRA7 alone and pVitro-SAG1-GRA7 with CpG-ODN three times at three-week intervals.
Background: Cutaneous leishmaniasis (CL) is one of the world health problems. is the etiological agent of zoonotic cutaneous leishmaniasis (ZCL). Promastigote and amastigote are two morphological forms of parasites that express different proteins and p27 is an important gene encoding cytochrome c oxidase (COX) component.
View Article and Find Full Text PDFBackground: Natural polysaccharides such as chitosan (CS) are widely used as antimicrobial agents. In recent years, and considering that CS has a strong antimicrobial potential, interest has been focused on antimicrobial activity of chitosan nanoparticles (CS NPs). The main factors affecting the antibacterial activity of chitosan include molecular weight (MW) and concentration.
View Article and Find Full Text PDFBackground & Objectives: Despite continuous global attempts to fight parasitic infections, malaria still remains one of the major human life threatening diseases. Difficulty of producing efficient antimalaria vaccines and increasing drug-resistant strains, highlight the urgent need to search for a new alternative antimalaria drug. The aim of this study was to find a new agent against malaria parasite with maximum efficacy and minimum range of side-effects.
View Article and Find Full Text PDF