Publications by authors named "Sara A Stickley"
Cell Host Microbe
October 2024
Article Synopsis
- The study investigates the impact of the human milk microbiota (HMM) on the long-term health of children, particularly focusing on asthma and allergic conditions like atopy.
- Researchers followed 885 mothers and their children from birth to age 5, linking HMM composition to the mothers' genetics and children's health outcomes.
- Findings suggest that certain bacterial communities in human milk, especially decreased diversity and increased Lawsonella, are correlated with higher rates of childhood atopy and asthma, highlighting the genetic influence on HMM composition.
Nat Commun
September 2024
Article Synopsis
- This study explores the relationship between maternal genetics, human milk oligosaccharides (HMOs), and respiratory health in infants fed human milk.
- Researchers quantified 19 HMOs from 980 mothers and identified genetic markers linked to HMOs on several chromosomes, including notable findings on chromosomes 19 and 3.
- The study suggests that certain HMOs may help reduce the risk of respiratory issues, like recurrent wheezing, in preschoolers, depending on their genetic predispositions.
