Synopsis of recent research by authors named "Sara A Murphy"
Sara A Murphy's recent research primarily focuses on cancer treatment through innovative therapies, particularly the application of oncolytic virus therapy and its interactions within the tumor microenvironment, as highlighted in studies examining IGF2 targeting and NOTCH signaling in brain tumors.
Additionally, her work on hearing conservation in military settings underscores the dose-response relationship between noise exposure and hearing loss, suggesting that current noise exposure standards may need revising to better protect service members.
Murphy's investigations into the role of histone modifiers in cancer biology further support the understanding of how epigenetic modulation can enhance the effectiveness of existing treatments, as demonstrated by her findings on ATF3 in synergy with protein disulfide isomerase inhibitors.