Publications by authors named "Sara A Aguirre-Diaz"

Article Synopsis
  • - The study examined Clostridioides difficile infection (CDI) trends and outcomes in 16 healthcare facilities in Mexico from 2016 to 2022, focusing on patient demographics and clinical data.
  • - Out of 2,356 CDI cases identified, 90% were healthcare-associated, with common comorbidities including hypertension and diabetes; the 30-day mortality rate was 16%.
  • - The findings highlight the need for improved surveillance and standardized CDI classification in Mexico, noting stable rates but differences in incidence between public and private hospitals.
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Monkeypox (Mpox) is a zoonotic viral infection endemic to Africa, which has caused a global outbreak since April 2022. The global Mpox outbreak is related to Clade IIb. The disease has primarily affected men who have sex with men.

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Background: Awake prone positioning (APP) reduces the intubation rate in COVID-19 patients treated by high-flow nasal cannula (HFNC). However, the lung aeration response to APP has not been addressed. We aimed to explore the lung aeration response to APP by lung ultrasound (LUS).

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Background: Awake prone positioning (APP) improves oxygenation in coronavirus disease (COVID-19) patients and, when successful, may decrease the risk of intubation. However, factors associated with APP success remain unknown. In this secondary analysis, we aimed to assess whether APP can reduce intubation rate in patients with COVID-19 and to focus on the factors associated with success.

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Objectives: To assess the effect of prone positioning therapy on intubation rate in awake patients with COVID-19 and acute respiratory failure.

Trial Design: This is a two-center parallel group, superiority, randomized (1:1 allocation ratio) controlled trial.

Participants: All patients admitted to the Hospital Civil de Guadalajara and Hospital General de Occidente in Mexico for COVID-19 associated acute respiratory failure and in need of supplementary oxygen through high-flow nasal cannula are screened for eligibility.

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Background: Clostridium difficile infection (CDI) is a leading cause of healthcare-associated diarrhea worldwide. Patients with chronic kidney disease (CKD) are especially vulnerable, as they are exposed to CDI risk factors including frequent antibiotics.

Materials And Methods: In order to identify the risk factors for CDI in CKD patients, a 33-month long case-control study was carried out at a tertiary-care hospital in Mexico.

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Background: Clostridium difficile infections caused by the NAP1/B1/027 strain are more severe, difficult to treat, and frequently associated with relapses.

Methods: A case-control study was designed to examine a C. difficile infection (CDI) outbreak over a 12-month period in a Mexican hospital.

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