Serum C-reactive protein and white blood cell level as markers of successful percutaneous drainage of acute sterile peripancreatic fluid collection.

Background: Percutaneous drainage is not a widely used therapeutic method recently for evacuating peripancreatic sterile fluid collections in patients with severe acute pancreatitis.However, many clinical studies have proved its positive effects.

Aim: We tested the changes in serum laboratory parameters:C-reactive protein (CRP), complement factor 3-4 (C 3-4),tumor necrosis factor a (TNF-a), amylase, lipase and white blood cell (WBC) count in patients treated by percutaneous drainage.

Autologous dendritic cell based adoptive immunotherapy of patients with colorectal cancer-A phase I-II study.

Dendritic cell-based active immunotherapies of cancer patients are aimed to provoke the proliferation and differentiation of tumor-specific CD4(+) and CD8(+) T-lymphocytes towards protective effector cells. Isolation and in vitro differentiation of circulating blood monocytes has been established a reasonable platform for adoptively transferred DC-based immunotherapies. In the present study the safety and tolerability of vaccination by autologous tumor cell lysates (oncolysate)- or carcinoembriogenic antigen (CEA)-loaded DCs in patients with colorectal cancer was investigated in a phase I-II trial.

Effects of various drugs (flunixin, pentoxifylline, enoxaparin) modulating micro-rheological changes in cerulein-induced acute pancreatitis in the rat.

Previously we have investigated the cerulein-induced acute pancreatitis and provided data on its micro-rheological impact in the rat. We hypothesized that non-steroid anti-inflammatory agent flunixin, the xanthine-derivate pentoxifylline and the low molecular weight heparin enoxaparin may have various beneficial effects improving microcirculatory and rheological parameters. In female rats, under general anesthesia, 10 μg/kg cerulein s.

Micro-rheological changes during experimental acute pancreatitis in the rat.

Although microcirculatory disturbances play pivotal role in the pathomechanism of acute pancreatitis (AP), very few papers can be found which had been tested any of hemorheological parameters. The aim of our study was to analyze the hemorheological changes in cerulein-induced experimental acute pancreatitis in rat in two doses (5 and 10 μg/kg, s.c.

Hepatobiliary response in postoperative lipid therapy in gastrointestinal surgery.

Background/aims: Intravenous lipid emulsions may contribute to the development of total parenteral nutrition (TPN)--induced hepatobiliary complications.

Methods: In a prospective, randomised setting the authors compared the short-term hepatic effects of medium-chain triglycerides/short-chain triglycerides (MCT/LCT) physical mixture with a four-component intravenous (i.v.

[Surgical treatment of acute pancreatitis today].

Unlabelled: In case of mild acute pancreatitis the treatment is basically conservative, but in severe cases surgical treatment has an important role.

Methods: authors analyze the indications for operation, the timing and the technical questions of it on the basis of the literature published in the previous ten years.

Results And Conclusions: sterile pancreas necrosis is rarely but septic necrosis is an indication for surgery if the conservative treatment is unsuccessful.

[Distal pancreas resection for metastasis of clear cell renal cancer].

Background: Distant spread from renal cell carcinoma is commonly found in the liver and lung. Metastatic involvement of any other gastro-intestinal organ (duodenum, other kidney, adrenal gland) is unexpected. However, clear cell renal carcinoma is known to cause pancreatic metastasis.

[Analysis of clinical course of severe acute biliary and non biliary pancreatitis: a comparative study].

Unlabelled: The acute pancreatitis is a relative common disease with incidence of 5-80 per 100000 people of the population. The number of new cases has steadily increased in recent years. The two main etiological factors are alcohol and cholelithiasis.

Hemorheological changes caused by intermittent Pringle (Baron) maneuver in beagle canine model.

In liver resection operations the Pringle (Baron) maneuver can be used for temporary ischemia by clamping the hepatoduodenal ligament intermittently. In this beagle canine model we investigated whether hemorheological parameters may alter in systemic, portal and hepatic venous blood and in arterial samples during-after Pringle maneuvers. In Pringle Group unilateral femoral artery and external jugular vein were cannulated.

Videothoracoscopic treatment of a rare complication of nasojejunal tube insertion.

Objective: Intubation of the tracheobronchial tree is the most common type of malposition during the placement of narrow-bore enternal tubes.

Case Report: In addition to other treatment components in a 65-year-old female, nasojejunal feeding was started to treat her for severe acute pancreatitis. After the placement of the narrow-bore feeding tube, she developed dyspnea and huskiness.

Surgical treatment of liver metastases from breast cancer.

Background/aims: The resection of colorectal liver metastases is currently a well accepted and effective treatment. In the past decade liver metastases of breast cancer have been treated more frequently by surgical intervention.

Methodology: The authors retrospectively studied the data of 17 operated patients, and investigated the clinical features of liver metastases, lymph node involvement of primary tumor, the indications of operations, and early and late results of the treatment.

Use of three lumen catheter facilitates bowel movement after pancreato-duodenectomy.

Background/aims: The advantages of jejunal nutrition in postoperative bowel paralysis following pancreato-duodenectomy were analyzed.

Methodology: Patients resected for pancreatic cancer received 25 kcal/kg/day and were followed up for 10 days postoperatively. Nasojejunal tube ensured enteral feeding in 16 patients (Gr.

Therapeutic tactics in the treatment of acute necrotizing pancreatitis.

Background/aims: The authors analyze the possibilities for the delay of surgery with special consideration regarding percutaneous peripancreatic drainage in the treatment of acute necrotizing pancreatitis.

Methodology: In addition to intensive care therapy, 61 patients were also given antibiotic prophylaxis, and early nasojejunal enteral feeding was commenced. In a total of 22 cases where peripancreatic fluid was found, percutaneous drainage was performed.

[Current issues in the diagnosis and treatment of penetrating chest trauma].

Introduction: Successful treatment of penetrating chest trauma largely depends on the accurate and rapid diagnostic work-up, as well as the adequate surgical management. The authors discuss current issues in the diagnosis and the treatment of penetrating chest injuries based on the analysis of 109 cases.

Patients And Methods: 82 men and 27 women with penetrating chest trauma were studied.

[The role of percutaneous external drainage in the treatment of fluid collections associated with severe acute pancreatitis. What, when and how to drain?].

The percutaneous drainage of the fluid collections associated with severe acute pancreatitis mainly in sterile cases is not a commonly accepted method. The aim of the present paper is to analyse the indications, the technic, the limits and results of the percutaneous drainage on the basis of the literature. The percutaneous drainage plays an important role in the treatment of the acute fluid collection, the acute pseudocyst, the pancreas abscess, and the liquified necrosis, accompanying the severe acute pancreatitis.

[Surgical management of sternoclavicular joint infections].

Aims: The pyogenic infection of the sternoclavicular joint is a rare disease. The treatment can be conservative (antibiotics) or surgical (exposure and drainage of the joint or its resection). The authors analyze the causative and predisposing factors, the symptoms, the diagnosis, the questions of the therapy and its efficiency.

[The role of VATS in the treatment of blunt thoracic injuries].

Aims: Video assisted thoracoscopy (VATS) is a more and more frequently used method in the diagnosis and treatment of blunt thoracic trauma. In some cases it has diagnostic and in others therapeutic effect. The authors analyze the role of VATS in the diagnosis and the treatment of 83 patients treated with haemothorax.

Mesohepatectomy without hilar dissection in the treatment of malignant focal liver diseases.

Background/aims: Mesohepatectomy is a method of surgical treatments for the centrally-located liver diseases. These operations were performed without hilar dissection by our modification and the results were evaluated.

Methodology: Between 2000 and 2002 we performed eight modified mesohepatectomy in cases of central malignant tumors of the liver.

[Balloon dilatation of cervical anastomosis stricture after subtotal resection of the esophagus].

Aims: The stricture of the anastomosis is one of the most common complications of the subtotal esophageal resections. The authors present indications, technics and results of the endoscopic dilatation.

Patients And Methods: In a 10 year period 26 patients (22 male, 4 female, mean age of 53.

Laparoscopic treatment of simultaneously occurring Morgagni and paraesophageal hernias.

A paraesophageal hernia was diagnosed in a 67-year-old female patient suffering from epigastric pain and gastroesophageal reflux disease. The patient underwent laparoscopy. Beside the paraesophageal hernia, a Morgagni hernia was also observed, with a significant part of the omentum herniated in the sac.

[Anterior approach for liver resection in the cases of the treatment of large liver tumors].

The authors compare the results of the patients who underwent right hemihepatectomy through anterior approach with those by conventional hemihepatectomy. In 119 patients hemihepatectomy was done, 52 of them were anterior approaches. We used this technique when the tumor was large, or it seemed to be fragile and its mobilisation could be dangerous or infiltrated the diaphragm or the the hepatic vein's preparation was difficult or impossible.