Publications by authors named "Sapunar A"
Aim: To determine if preoperative treatment with a topical non-steroidal anti-inflammatory drug (NSAID) lowers the concentration of intraocular interleukin (IL)-12 and the incidence of postoperative macular edema in patients with non-proliferative diabetic retinopathy undergoing cataract surgery.
Methods: A total of 55 patients were randomized to diclofenac (n=27) or placebo (n=28). Patients receiving diclofenac started preoperative treatment with 0.
Parents frequently bring their children to the Emergency Department (ED) because of the fever without apparent source (FWAS). To avoid possible complications, it is important to recognize serious bacterial infection (SBI) as early as possible. Various tests, including different clinical scores and scales, are used in the laboratory evaluation of patients.
View Article and Find Full Text PDFBackground: Testicular flow studies after hernia mesh repair mostly showed different outcomes. The reason of infertility in some men after hernia repair is immunological factors. Aim of the study was to investigate the influence of mesh hernia repair on antisperm antibodies production and testicular blood flow and a connection among these parameters.
View Article and Find Full Text PDFBackground: The incidence of infertility caused by the mesh inguinal hernia repair is not known. The aim of this study was to determine circulation and immunological testicular disorders after inguinal hernia mesh repair which can be related with infertility.
Methods: From February 2010 to December 2010, 43 male patients who underwent inguinal hernia mesh repair were included in a prospective study.
IL-12 concentrations in the aqueous humor and serum of diabetic retinopathy patients.
Graefes Arch Clin Exp Ophthalmol
June 2012
Article Synopsis
- Inflammation is implicated in diabetes progression, with interleukin 12 (IL-12) identified as a key pro-inflammatory cytokine.
- A study involving 76 participants found that IL-12 concentration was significantly higher in the aqueous humor of diabetic patients with non-treated retinopathy compared to other groups.
- The serum IL-12 levels did not show significant variation among the groups, suggesting local production of IL-12 in the eye rather than systemic changes.
A high prevalence of epilepsies in specific immunological diseases suggests that the immune system may play a role in the pathogenesis of epilepsy or might be associated with it. In this study the frequency of anticardiolipin antibodies (aCL), antinuclear antibodies (ANA) and anti-beta2-glycoprotein I antibodies (anti-beta2-GPI) in 40 children with epilepsy and in 38 healthy subjects was determined. Positive aCL was found in 3 patients, and anti-beta2-GPI in 1 patient.
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- The study aimed to investigate the prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Komiza on the island of Vis, known for its cases of favism.
- Researchers screened 302 men using a fluorescent spot test, later corroborating results with a quantitative UV method.
- The findings revealed that 5.96% of the men were G6PD deficient, notably higher than the 0.75% prevalence in Dalmatia, suggesting the need for newborn screening for G6PD deficiency on the island and further studies in the region.
The authors describe the peripheral blood analyses in patients splenectomized for trauma in consideration on the concentration of the immunoglobulins total complement CH50 levels, T and B lymphocyte populations and compare this with the control group. The levels of the IgM were significantly decreased (p0.001) in splenectomised while the levels of the IgA and IgG were significantly increased (for IgA - p0.
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