Publications by authors named "Sapna Vyakaranam"

Article Synopsis
  • - The Asian Indian Beta Cell function (ABCs) in Infants Study focused on how maternal weight during pregnancy impacts infant pancreatic beta cell function at 7 months after childbirth, recruiting women of different BMI categories in Hyderabad, India.
  • - Infants underwent an oral glucose tolerance test, revealing a U-shaped relationship between maternal weight and beta cell function, with greater function observed in infants of underweight and normal weight mothers compared to those of overweight mothers.
  • - At 7 months, infants displayed significant changes in insulin resistance based on maternal weight, with the highest insulin resistance reduction in infants of underweight mothers, while those from normal weight mothers had the highest disposition index, indicating better beta cell function.
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Vitamin D deficiency in known to be high in obese and overweight adolescents. Few studies in other countries have shown lower parathyroid hormone (PTH) levels in obese adolescents despite high vitamin D deficiency. The aim of the study is to assess vitamin D and PTH levels and their relationship in overweight and obese adolescents in Telangana.

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Background: Hypoxia driven oxidative stress of the placenta contributes to the pathogenesis of preeclampsia. Serum Ischemia Modified Albumin (IMA) has recently emerged as an oxidative stress marker, used in diagnosis of cardiac ischemia. Aim: To determine the efficiency of serum IMA in differentiating hypertensive disorders of pregnancy (pregnancy induced hypertension, preeclampsia) from normal pregnancy.

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Background: Thyroid hormones influences glucose homeostasis. The association of insulin resistance in overt hypothyroidism is well proven, but very less information is available about insulin action on subclinical hypothyroidism.

Objective: This study was done to evaluate the association between thyroid hormones and insulin resistance in subclinical hypothyroidism (SCH).

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Background: Renal dysfunction, increased xanthine oxidase activity and oxidative stress in placenta contributes to the elevated uric acid levels in preeclampsia (PE).

Objective: To determine serum uric acid and creatinine in hypertensive disorders of pregnancy and correlate with fetal outcome.

Materials And Methods: Pregnant women ≥32 weeks of gestation.

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