Publications by authors named "Sapir Pinyan"
Article Synopsis
- The study investigates how glycosphingolipids (GSLs), specifically α1,2-fucosylated GSLs, influence the differentiation of human pluripotent cells (hPCs) during early embryogenesis.
- Overexpression of these GSLs hinders hPC differentiation into mesodermal cells and cardiomyocytes, while their reduction enhances differentiation and responsiveness to external signals such as BMP4.
- The research suggests that α1,2-fucosylated GSLs play a crucial role in regulating cell signaling pathways involved in early embryo development and cell fate decisions.
