Psychological Status as an Effect Modifier of the Association Between Allergy Symptoms and Allergy Testing.

Objective: Patient-reported outcome measures, while valuable, may not correlate with diagnostic test results. To better understand this potential discrepancy, our objective was to determine whether psychological health is an effect modifier of the association between patient-reported allergy outcome scores and allergy test results.

Study Design: Prospective outcomes study.

Biologics versus endoscopic sinus surgery: Acute rhinosinusitis episodes and antibiotic use in chronic rhinosinusitis.

Background: We sought to determine if chronic rhinosinusitis patients treated with endoscopic sinus surgery have fewer episodes of acute rhinosinusitis (ARS) post treatment compared to CRS patients treated with biologics alone.

Methods: We analyzed the electronic medical records of 213 adults with CRS who initiated treatment with either dupilumab or mepolizumab in calendar years 2016-2021 (CRS-biologics) group and a matched group with tissue eosinophilia who had undergone endoscopic sinus surgery (CRS-ESS) group. For each cohort, the medical record was reviewed to determine the number of ARS episodes for 12 months before and after treatment.

A case report of sinonasal glomangiopericytoma: An important reminder to always collect specimen.

Objectives: To present a case report of sinonasal glomangiopericytoma (GPC) in a female patient in her thirties and to highlight the importance of collecting pathology specimens even in routine sinus surgery cases.

Methods: A case report detailing the diagnosis of GPC in a female in her thirties, including her initial presentation, treatment, and follow-up, along with a brief review of the literature.

Results: Pathology of the collected specimen revealed sinonasal GPC along with chronic rhinosinusitis.

Parathyroidectomy outcomes for Asians in the United States: Implications for resident surgical education.

Introduction: Outcomes for Asian patients in the United States are often overlooked in the surgical literature. Surgical education includes little emphasis on reporting outcomes for Asian patients in the United States. Our null hypothesis (H) is that there is no difference in surgical complications following parathyroid surgery between Asians and all other ethnicities in the United States.

Epidemiology, etiology, genetic variants in non- syndromic hearing loss in Iran: A systematic review and meta-analysis.

Objectives: Hearing loss is one of the most common heterogeneous complicated disorders worldwide. We previously analyzed the results of published data on non-syndromic hearing loss in the Iranian population systematically. A broad range of genes is a challenge for molecular screening and clinical diagnosis in our populations on the ground of distinct genetics.

Reducing Surgical Risks for Septal and Turbinate Surgery.

Septoplasty is one of the most frequently performed procedures in otolaryngology. The procedure is also performed by oral and maxillofacial surgeons as well as plastic surgeons. Septal deviation is one of the most common findings on physical examination in the otolaryngologist's office.

Rethinking the relationships between chronic rhinosinusitis and asthma severity.

Background: Previous authors have endorsed the need for prospective studies on the effect of treatment of chronic rhinosinusitis on asthma outcomes. Although common pathophysiology for asthma and chronic rhinosinusitis (CRS) has been suggested with the unified airway theory, there is limited data to support the claim and our study does not support the theory.

Methods: This case-control study involved adult patients with a primary diagnosis of asthma in 2019 who were identified from the electronic medical records and divided into those with and without an associated CRS diagnosis.

Seven cardinal questions for the patient with ear, nose or throat complaints: Review.

The incidence of otolaryngological problems in general medicine practice is highly seasonal and approaches 25% in some months of the year. Accurate diagnosis in the otolaryngology office often requires the use of binocular microscopy, nasal endoscopy, and flexible laryngoscopy, none of which are available in a general medicine office. Therefore, history taking and physical examination techniques available in the non-otolaryngology office are of utmost importance.

The Potential Protective Effects of Statins in Chronic Rhinosinusitis: A Case-Control Study.

Objectives/hypothesis: To determine the potential protective effect of prior statin use on the subsequent diagnosis of chronic rhinosinusitis (CRS).

Study Design: Retrospective, case-control.

Methods: Electronic medical records for all patients seen in the otolaryngology clinic in 2019 and receiving a diagnosis of CRS were reviewed for the presence or absence of active prior statin use within 365 days of the visit.

COVID-19 and anosmia in Tehran, Iran.

Patients with acute olfactory disorders typically present to the otolaryngologist with both acute hyposmia and less often with anosmia. With the onset of COVID-19 we have noticed an increase in the number of patients who have presented with new onset of complete smell loss to the senior author's practice in Tehran, Iran. This anosmia and the frequency with which patients present is highly unusual.

Electronic Consults in Otolaryngology: A Pilot Study to Evaluate the Use, Content, and Outcomes in an Academic Health System.

Objectives: To categorize the primary reasons for electronic consults (eConsults) to otolaryngology from primary care physicians (PCPs). To determine how many patients avoided subsequent in-person otolaryngology office visits.

Methods: This is a retrospective analysis of a pilot study that took place between 2016 and 2017 regarding eConsults to adult otolaryngology placed by primary care physicians at the University of California, San Diego (UCSD) Medical Center.

Revisit Rates for Pediatric Tonsillectomy: An Analysis of Admit and Discharge Times.

Objective: To determine the association between intraday timing of outpatient pediatric tonsillectomy and revisit outcomes and complications.

Study Design: Cross-sectional analysis of New York databases.

Setting: Ambulatory surgery, emergency department and inpatient hospital settings.

Time and geographic clustering of adult patients with unilateral idiopathic sudden sensorineural hearing loss.

For the preponderance of patients with unilateral idiopathic sudden sensorineural hearing loss (SSNHL), the etiology is unknown. The pathogenesis of disease and a definitive mechanism for this abrupt hearing loss has not yet been elucidated. We hypothesize that there is a time-clustered presentation for idiopathic SSNHL; from an epidemiological standpoint, this suggests an environmental or infectious etiology.

Perioperative Risk Factors Associated With Morbidity and Mortality Following Pediatric Inpatient Sinus Surgery.

Objectives:: Pediatric sinus surgery is indicated for a wide range of sinonasal and skull base pathologies, but it is most commonly performed for recalcitrant chronic rhinosinusitis or complicated acute sinusitis. The authors aim to report medical risk factors of morbidity and mortality following inpatient sinus surgery in the pediatric population.

Methods:: Using data from the Kids' Inpatient Database from 2003 to 2012, patients with International Classification of Diseases, Ninth Revision, procedure codes for primary sinus surgery were identified.

Factors Predictive of Postoperative Acute Respiratory Failure Following Inpatient Sinus Surgery.

Objective: The impact of perioperative risk factors on outcomes following outpatient sinus surgery is well defined; however, risk factors and outcomes following inpatient surgery remain poorly understood. We aimed to define risk factors of postoperative acute respiratory failure following inpatient sinus surgery.

Methods: Utilizing data from the Nationwide Inpatient Sample Database from the years 2010 to 2014, we identified patients (≥18 years of age) with an Internal Classification of Disease, Ninth Revision, Clinical Modification (ICD-9-CM) procedure code of sinus surgery.

Prevalence of Potential Adult Chronic Rhinosinusitis Symptoms in the United States.

Objective To determine the prevalence of chronic rhinosinusitis-related symptoms in the United States. Study Design Cross-sectional analysis of a national database. Setting Representative sampling of the US adult population.

The Burden and Visit Prevalence of Pediatric Chronic Rhinosinusitis.

Objectives Pediatric chronic rhinosinusitis has a substantial impact, but its epidemiology has yet to be elucidated. Our objectives were (1) to determine the associated national visit burden and (2) to assess its frequency relative to other frequent childhood otolaryngological illnesses. Study Design Analysis of national survey databases.

Grade repetition and parents' perception of hearing loss: An analysis of data from children in the United States.

Objectives/hypothesis: To determine whether parent-perceived hearing problems are associated with grade repetition among children in the United States.

Study Design: Retrospective cohort analysis of a contemporary national database.

Methods: The National Survey of Children's Health 2011 to 2012 was analyzed.

National Practice Patterns of Antireflux Medication for Chronic Rhinosinusitis.

Importance: Antireflux medication has been endorsed as a useful adjunctive therapy for chronic rhinosinusitis, but its use remains controversial.

Objectives: To determine whether chronic rhinosinusitis is associated with administration of proton pump inhibitors, histamine2-receptor antagonists, antacids, or prokinetic agents; whether practice patterns vary according to visit setting; and whether those patterns vary according to the presence or absence of potentially confounding conditions.

Design, Setting, And Participants: A cross-sectional analysis was performed of data from January 1, 2005, to December 31, 2010, from the National Ambulatory Medical Care Survey and National Hospital Ambulatory Medical Care Survey, which included 590 772 observations representing 7 191 711 480 ambulatory care visits.

Obstructive Sleep Apnea and Gastroesophageal Reflux: A Multivariate Population-Level Analysis.

Objectives: Previous studies investigating the relationship between gastroesophageal reflux (GER) and obstructive sleep apnea (OSA) demonstrate mixed results and have had limited capacity to control for concurrent confounders. Our objectives were to (1) determine if GER is significantly associated with OSA when simultaneously adjusting for the presence of other potentially confounding conditions and (2) quantify the magnitude of any such association that exists.

Study Design: Cross-sectional analysis of the National Ambulatory Medical Care Survey and National Hospital Ambulatory Medical Care Survey, 2005-2010.

High grade neuroendocrine neoplasm of the antrum and orbit.

Neuroendocrine malignancies-tumors characterized by the production of dense-core secretory granules-are most often encountered in the lungs and can also be found in extrapulmonary sites. Our patient had a primary neuroendocrine tumor of the antrum with an elusive cell of origin that secondarily invaded the inferior orbit. In the sinuses, neuroendocrine tumors may be confused with infectious sinusitis or squamous cell carcinoma.

Diagnostic yield of MRI for pediatric hearing loss: a systematic review.

Objective: To perform a systematic review to analyze the diagnostic yield of magnetic resonance imaging (MRI) for pediatric hearing loss, including comparison to computed tomography (CT) and subgroup evaluation according to impairment severity and specific diagnostic findings (cochlear anomalies, enlarged vestibular aqueduct, cochlear nerve abnormalities, and brain findings).

Data Sources: Pubmed, EMBASE, and the Cochrane library were assessed from their inception through December 2013. Manual searches were also performed, and topic experts were contacted.

Risk of malignancy associated with head and neck CT in children: a systematic review.

Objective: To perform a systematic review to evaluate the risk of malignancy associated with computed tomography (CT) of the head and/or neck in infants, children, and adolescents.

Data Sources: Pubmed, EMBASE, and the Cochrane Library were assessed from the date of their inception to January 2014. Additionally, manual searches of bibliographies were performed and topic experts were contacted.

Personally Modifiable Risk Factors Associated with Pediatric Hearing Loss: A Systematic Review.

Background: Pediatric hearing loss is an increasingly recognized problem with significant implications. Increasing our quantitative understanding of potentially modifiable environmental risk factors for hearing loss may form the foundation for prevention and screening programs.

Objective: To determine whether specific threshold exposure levels of personally modifiable risk factors for hearing loss have been defined, with the overarching goal of providing actionable guidance for the prevention of pediatric hearing loss.