L mitigates bisphenol A-induced ovarian dysfunction and inflammation in Wistar rats: biochemical, histopathological, pharmacokinetic, and in silico studies.

The present study evaluated the antioxidant and anti-inflammatory properties of (CA) fruit extract against bisphenol A (BPA)-induced ovarian injury in female Wistar rats. The antioxidant activity was estimated by the total antioxidant capacity (TAC) and superoxide radical (NBT) content. For the in vivo analyses, 24 animals were divided into the following 4 groups: the control group; the BPA group (50 mg/kg BW BPA for 30 days); the BPA  + CA group (50 mg/kg BW BPA and 50 mg/kg BW CA); and the CA group (50 mg/kg BW CA).

GC-MS/MS Analysis and Wound Repair Potential of Urtica dioica Essential Oil: In silico Modeling and In vivo Study in Rats.

Background: The study aimed to assess the antioxidant and wound healing properties of Urtica dioica essential oil (UDEO) through a comprehensive evaluation involving in silico, in vitro, and in vivo analyses. The phytochemistry of UDEO was also investigated to identify trace compounds crucial.

Methods: Various injection methods of the multimode inlet (MMI) in chromatography were investigated to attain lower instrumental detection limits.

: Evaluation of Chemical Nature of Metabolites and Their Antioxidant and Agronomics Properties.

is particularly known for its abundance in soils and its plant growth promotion. To characterize the metabolites excreted by this specie, we performed successive liquid/liquid extractions from bacteria culture medium with different polarity solvents (cyclohexane, dichloromethane, ethyl acetate and butanol) to separate the metabolites in different polarity groups. The extracts were characterized regarding their total phenolic content, the amount of reducing sugar, the concentration of primary amines and proteins, their chromatographic profile by HPLC-DAD-ELSD and their chemical identification by GC-MS.

Antioxidant and antiproliferative effects of extract: computational and study in rats.

The current study aimed to assess the antioxidant and antiproliferative effects of extract: computational and study in rats. Three groups of animals: Group (i) constitute the control group; Group (ii) HeLa group received an intrafemoral inoculation of HeLa cells and Group (iii) constitue the combination between HeLa + . The plant was administered by gavage.

Analysis of Antioxidant and Antiviral Effects of Olive ( L.) Leaf Extracts and Pure Compound Using Cancer Cell Model.

The present study aims to assess the antioxidant and antiviral effectiveness of leaf extracts obtained from L. var. and L.

Phytochemical Composition of Urtica dioica Essential Oil with Antioxidant and Anti-inflammatory Properties: In Vitro and In Vivo Studies.

Background: Urtica dioica (Urticaceae) has outstanding medicinal and pharmacological properties. This investigation was aimed to assess the chemical composition, the total polyphenol and flavonoid content, antioxidant, anti-proliferative, and anti-inflammatory effects of Urtica dioica essential oil (UDEO)

Methods: GC/MS analysis was performed to assess the chemical composition, standard antioxidative test, the DPPH assay, the reducing power assay, as well as the anti-proliferative capacities of UDEO against HeLa cell lines using the MTT test. In addition, the anti-inflammatory activities of UDEO were evaluated using paw thickness measurements in rats with carrageenan-induced paw edema and pathologic evaluation of inflammation in paw sections.

Correction: Saoudi et al. The Role of L. in the Attenuation of Dermal Wounds by Modulating Oxidative Stress and Inflammation in Albino Rats. 2021, , 4875.

The authors wish to make the following change to their paper [...

Mechanisms governing the dissolution of phosphorus and iron in sewage sludge by the bioacidification process and its correlation with iron phosphate speciation.

In the last two decades, phosphorus (P) recovery from sewage sludge liquors gained much interest for its high-quality product potential. However, the consistently reported constraints are the low phosphorus availability and the technical-economical difficulties to increase it through chemical acidification. This article discusses the mechanisms of phosphorus dissolution by the biological acidification process (Biological acidification or acidic fermentation) as an alternative to chemical acidification.

Attenuation of ovalbumin-induced inflammation and lung oxidative injury in asthmatic rats by extract: combined in silico and in vivo study on antioxidant potential, STAT6 and TNF- pathways.

In the present study we focused on the anti-asthmatic and antioxidant effects of L. (ZO) aqueous extract. This study includes 20 adult male rats, which were grouped into four; Group I: control group; Group II: asthmatic group (Ovalbumin sensitized/challenge model, Oval group); Group III: received ovalbumin sensitized/challenge associated a dose of 207 mg/kg body weight (BW) of ZO (Oval + D1 group); Group IV: received ovalbumin sensitized/challenge associated a dose of 414 mg/k BW of ZO (Oval + D2 group).

Pharmacokinetics and Therapeutic Potential of against Liver Damage Associated Hepatotoxicity and Oxidative Injury in Rats: Computational, Biochemical and Histological Studies.

This study investigated the druggability, pharmacokinetics and ethyl acetate extract of (EA ) and the protective effect against carbon tetrachloride (CCl) induced liver cirrhosis in rats. The total antioxidant capacity (TAC) and scavenging activity of the extract were examined. The in vivo protective study was based on the use of an animal model of CCl-induced liver cirrhosis.

Antiviral Effects of Artemisinin and Its Derivatives against SARS-CoV-2 Main Protease: Computational Evidences and Interactions with ACE2 Allelic Variants.

Fighting against the emergent coronavirus disease (COVID-19) remains a big challenge at the front of the world communities. Recent research has outlined the potential of various medicinal herbs to counteract the infection. This study aimed to evaluate the interaction of artemisinin, a sesquiterpene lactone extracted from the genus, and its derivatives with the SARS-CoV-2 main protease.

Correlation between phosphorus removal technologies and phosphorus speciation in sewage sludge: focus on iron-based P removal technologies.

Phosphorus recovery from sewage sludge as secondary raw materials or as a direct P-rich fertiliser is one of the top frontrunner solutions to tackle Phosphorus (P) scarcity and depletion. However, the efficiency of this P recovery process greatly depends on its phosphorus dissolution potential, which in return relies on the phosphorus speciation in the sewage sludge. This article investigates the potential correlation between P speciation in sewage sludge and the iron-based P removal technologies used in sewage treatment plants (STP) through an innovative sequential extraction method based on the SEDEX method that distinguishes quantitatively between ferrous bound phosphate and ferric bound phosphate.

Expression Profiling of Selected Immune Genes and Trabecular Microarchitecture in Breast Cancer Skeletal Metastases Model: Effect of α-Tocopherol Acetate Supplementation.

Breast cancer bone metastases (BCBM) result in serious skeletal morbidity. Although there have been important advances in cancer treatment methods such as surgery and chemotherapy, the complementary treatments, such as α-tocopherol acetate (ATA), still remain of key role via complementary and/or synergistic effects. The aim of this work was to study immune response in a rat model of BCBM due to Walker 256/B cells inoculation and the effect of ATA alone.

Therapeutics studies and biological properties of Teucrium polium (Lamiaceae).

Teucrium polium has been used in traditional medicine as antifungal, antipyretic, antispasmodic, and antibacterial. It is consumed by many jordanians for the treatment of many diseases. The effects of this plant have been investigated in kidney, liver, and brain.

Phenolic Compounds of L. Extracts and Their Effect as Antioxidant and Cytotoxic Activities.

L. () is acknowledged as an aromatic plant. For its excellent biological properties, it was used as a traditional medicine.

Polyaniline: Doping and Functionalization with Single Walled Carbon Nanotubes for Photovoltaic and Photocatalytic Application.

Polyaniline (PANI) was chemically doped and functionalized with single walled carbon nanotubes (SWCNTs). Various characterization methods were employed to study the structure and optical properties of PANI/SWCNTs nanocomposite, such as Fourier transform infrared (FTIR), differential scanning calorimetry (DSC), scanning electron microscopy (SEM), optical absorption, and stationary photoluminescence. Additionally, a theoretical study using density functional theory calculations was also carried out.

The Role of L. in the Attenuation of Dermal Wounds by Modulating Oxidative Stress and Inflammation in Albino Rats.

In our study, L. (AS) was investigated to assess its phenolic profile and bioactive molecules including flavonoids and organosulfur compounds. The antioxidant potential of AS and wound healing activity were addressed using skin wound healing and oxidative stress and inflammation marker estimation in rat models.

Phytochemical Composition, Antioxidant, Antiacetylcholinesterase, and Cytotoxic Activities of L.

L. () is regarded as an aromatic plant. It was used for its excellent biological properties in traditional medicine.

Antioxidant and Protective Effects of Essential Oil Against Chlorpyrifos-Induced Kidney and Liver Injuries in Rats.

This study is aimed to elucidate the possible antioxidant and protective effects of essential oil (ACEO) against the deleterious effects of chlorpyrifos (CPF) in rats. The study revealed increases in aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and alkaline phosphatase (ALP) activities and the serum contents of creatinine, urea, uric acid, cholesterol, triglycerides, low density lipoproteins (LDL), and glucose in rats treated with CPF as compared to controls. Meanwhile, hepatic and renal activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in liver and kidney decreased and the content of malondialdehyde (MDA) increased.

Use of fermentation processes for improving the dissolution of phosphorus and its recovery from waste activated sludge.

Recycling phosphorus from waste activated sludge has attracted a lot of interest to tackle the problem of phosphorus stocks depletion and the increase in food demand. In this study, the use of fermentation processes was investigated to enhance phosphorus dissolution from waste activated sludge to improve its recycling. Two fermentation processes, bioacidification and dark fermentation, were used on two different sludges fermented with wheat starch syrup in continuous operating conditions.

Development of a Polarizable Interatomic Potential for Molten Lithium, Sodium, and Potassium Nitrate.

A polarizable interatomic potential is developed for atomistic simulations of molten MNO (M = Li, Na, K) salts. The potential is parametrized using a force matching method relying on the adjustment of parameters such that density functional theory generated forces, stress tensors, and dipole moments are reproduced. Simulations conducted using the new potential are used to estimate physical parameters of the melt, which are then compared with available experimental results.

Beneficial effects of crataegus oxyacantha extract on neurobehavioral deficits and brain tissue damages induced by an insecticide mixture of deltamethrin and chlorpyrifos in adult wistar rats.

Pesticides, such as organophosphorus and pyrethroids, are extensively used in the agrofields which can significantly increase crop productivity. Humans are exposed to pesticides via dermal contact, inhalation and ingestion due to occupational exposure. The objective of the present study was to evaluate the protective role of the aqueous extract of Crataegus oxyacantha during acute exposure of rats to the combination of deltamethrin (DM) and chlorpyrifos (CPF) in rats (DCF).

Hepatotoxicity and nephrotoxicity in rats induced by carbon tetrachloride and the protective effects of Teucrium polium and vitamin C.

This work investigated the protective effects of Teucrium polium (T. polium) and vitamin C (Vit C) against carbon tetrachloride (CCl) induced hepatotoxicity and nephrotoxicity in rats. T.

Biochemical and microbial changes reveal how aerobic pre-treatment impacts anaerobic biodegradability of food waste.

Aerobic pre-treatment of food waste (FW) was performed at different oxygen concentrations (0%, 5%, 10% and 21%O) and different durations (1, 2, 3 and 4 days) to investigate its impact on biochemical and microbial community characteristics of the waste and its ability to improve anaerobic biodegradability. Whatever the duration, the highest effect of pre-treatment was observed at full aerobic pre-treatment (21%O) while 5%O and 10%O showed lower transformation performances. Biochemical variations at 21%O were mainly a decrease of simple carbohydrates, volatile fatty acids (VFA) and low molecular weight water soluble compounds and an increase of high weight water soluble compounds.

Valorisation of tuna processing waste biomass: isolation, purification and characterisation of four novel antioxidant peptides from tuna by-product hydrolysate.

Tuna protein hydrolysate (TPH) was prepared by hydrolysis with Prolyve BS and fractionated by membranes process. The antioxidant activities of recovered peptide fractions were evaluated. Four novel antioxidant peptides that were isolated from nanofiltration retentate exhibited the highest antioxidant activity, using gel chromatography and reversed phase high-performance liquid chromatography.