A voltammetric sensor has been developed for the individual as well as simultaneous determination of xanthine (XA) and hypoxanthine (HX) based on an electroactive-polymerised layer of para toluene sulphonic acid and gold nanoparticles composite modified glassy carbon electrode ([p(PTSA)]/AuNPs/GCE)]. Under optimized conditions, an enhancement in the oxidation currents with well-separated and well-resolved peak position and a lower shift in the peak potentials were observed. By square wave voltammetry, the simultaneous determinations of XA and HX were achieved in the linear ranges 6.
View Article and Find Full Text PDFA 24-year-old female with pneumonia two months prior presented with fever, cough, and worsening dyspnoea in the midst of a COVID-19 spike. Her initial episode was treated as COVID-19 pneumonia. On presentation, her chest computed tomography was suggestive of bilateral lower zone organising pneumonia with mild fibrosis and was attributed to post-COVID sequelae with an infective exacerbation.
View Article and Find Full Text PDFFor the first time, we report on a copper nanoclusters based fluorescence sensor for hemoglobin (Hgb). The aggregation-induced quenching of tannic acid capped copper nanoclusters' (TACuNCs) fluorescence by a Hgb-HO mixture that mimics the Fenton's reagent is used here for the selective determination of Hgb. It is possible to effectively determine Hgb using this sensitive and cost-effective sensor in the linear range of 5.
View Article and Find Full Text PDFA simple and selective 'turn-on' fluorescence sensor have been developed for the determination of xanthine (XA) based on glutathione (GSH) capped copper nanoclusters (CuNCs) as the fluorescent probe. The proposed sensor possess several advantages such as sensitivity, short analysis time and requires no sample pretreatment. The conditions for the performances of the sensor have been optimized and good linear relationship was obtained between concentration and relative fluorescence intensity in the concentration range 9.
View Article and Find Full Text PDFThe present article reports the efficiency of L-cysteine modulated copper nanoclusters (L-cys-CuNCs) as a fluorescent probe for the selective determination of naturally occurring bile pigments biliverdin (BVD) and bilirubin (BLR). These pigments were found to quench the fluorescence of L-cys-CuNCs through static processes. Under optimized conditions, the proposed strategy permitted the quantification of BVD and BLR in the range 4.
View Article and Find Full Text PDFPerioperative prophylactic antibiotics following surgeries have been shown to reduce surgical site infections, and their administration is common practice. Despite clear guidelines regarding this being set forth by the Infectious Disease Society of America (IDSA), adherence to them is yet to translate to common practice in many parts of the world. A retrospective chart review of 409 patients who underwent elective surgeries over a period of 7 months at three different hospitals in India was performed.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
April 2019
The present paper reports l-cysteine functionalized CdS quantum dots (QDs) as a simple and highly selective turn-off fluorescence sensor for the determination of tetracycline (TET). The unauthorized use of TET may pose serious health hazards in human beings and hence the detection and determination has become very essential. In this regard, we have developed a sensor that enable the quantification of TET in the range 6.
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