There are few ambient air measurements of extended lists of carcinogenic polycyclic aromatic hydrocarbons (cPAHs); which are pollutants useful in source identification and significant contributors to cumulative inhalation cancer potency. We present findings from a multi-year ambient air sampling study with comparisons of cancer risk estimates for monitoring sites influenced by a variety of sources based on Minnesota Department of Health guidance. Cancer risks were calculated from raw cPAH measurements and cPAH measurements adjusted by wind direction to reflect the full potential impact of the facility's air emissions.
View Article and Find Full Text PDFBackground: Chronic tension type headache (CTTH) is one of the common cause of hospital visits among adolescents and adults. Chronic tension type headache produces pain, sleep disturbances, and disability among patients leading to a poor quality of life. Knowledge pattern of headache and various associated factors will aid appropriate management.
View Article and Find Full Text PDFPurpose: To present a case series of zygomatic implants combined with bone regeneration and soft tissue enhancement techniques to reduce the risk of biological delayed complications such as maxillary sinusitis and soft tissue recession.
Materials And Methods: Zygomatic implants placed simultaneously with different bone regeneration techniques (buccal, palatal and buccal-palatal bone regeneration) and soft tissue enhancement techniques (pediculate and free connective tissue graft) were followed for at least 12 months. The following information was collected: patient age and sex, number of zygomatic implants, zygomatic implant success rate, zygomatic implant position according to classification of the Zygomatic Anatomy Guide Approach (ZAGA), sinus membrane perforation, type and outcome of the bone regeneration or the soft tissue enhancement technique, bone gain (width and length along the zygomatic implant) and keratinized buccal mucosa width, duration of follow-up, loading protocol (immediate or delayed) and biological complications (maxillary sinusitis and soft tissue recession).
: Bladder cancer is the second most common genitourinary tract cancer and is often recurrent and/or chemoresistant after tumor resection. Cigarette smoking, exposure to aromatic amines, and chronic infection/inflammation are bladder cancer risk factors. NF-κB is a transcription factor that plays a critical role in normal physiology and bladder cancer.
View Article and Find Full Text PDFGastrointestinal (GI) cancers are known to have a high incidence worldwide and require an early diagnosis to successfully treat them, providing higher survival rates and better quality of life for the patients. MicroRNA-27a is a well-known oncogene that plays a significant role in various GI cancers. It is known to upregulate the expression of numerous oncogenes leading to cancer progression.
View Article and Find Full Text PDFJ Indian Soc Pedod Prev Dent
March 2020
Oral squamous papillomas are benign proliferating lesions induced by human papillomavirus. These lesions are painless and slowly-growing masses. As an oral lesion, it raises concern because of its clinical appearance.
View Article and Find Full Text PDFIn the contemporary practice of palladium catalysis, a molecular understanding of the role of vital additives used in such reactions continues to remain rather vague. Herein, we disclose an intriguing and a potentially general role for one of the most commonly used silver salt additives, discovered through rigorous computational investigations on four diverse Pd-catalyzed C-H bond activation reactions involving sp aryl C-H bonds. The catalytic pathways of different reactions such as phosphorylation, arylation, alkynylation, and oxidative cycloaddition are analyzed, with and without the explicit inclusion of the silver additive in the respective transition states and intermediates.
View Article and Find Full Text PDFBackground: High affinity sodium-dependent Excitatory Amino Acid Transporters (EAAT), present in glial and neuron cells, clear around 90% of the synaptic cleft released glutamate, and their impaired activity seem to be critical for many neurodegenerative disorders, including Multiple Sclerosis (MS). These transporters are also present in human platelets, and they show molecular and biochemical characteristics similar to those in the CNS.
Objectives: The aim of this study was to investigate whether EAAT-dependent uptake is present also at the peripheral level in blood of MS patients.
Background And Aim: Assessment of dentofacial asymmetries and other discrepancies that can affect the horizontal reference lines should be considered initially as a part of the esthetic diagnosis. Some variations of facial asymmetry are not considered an esthetic liability. So the aim of the present study is to determine a layperson's preference regarding transverse occlusal plane (TOP) orientation in fabrication of a complete denture.
View Article and Find Full Text PDFRNA-Seq technology was used to analyze the transcriptome of two rice hybrids, Ajay (based on wild-abortive (WA)-cytoplasm) and Rajalaxmi (based on Kalinga-cytoplasm), and their respective parents at the panicle initiation (PI) and grain filling (GF) stages. Around 293 and 302 million high quality paired-end reads of Ajay and Rajalaxmi, respectively, were generated and aligned against the Nipponbare reference genome. Transcriptome profiling of Ajay revealed 2814 and 4819 differentially expressed genes (DEGs) at the PI and GF stages, respectively, as compared to its parents.
View Article and Find Full Text PDFJ Assoc Physicians India
January 2020
J Assoc Physicians India
January 2020
J Assoc Physicians India
January 2020
J Assoc Physicians India
January 2020
Annu Int Conf IEEE Eng Med Biol Soc
July 2019
In most cases, high energy solid state lasers such as Nd:YAG are used as source of illumination for Photoacoustic Tomography (PAT). However the bulkiness, high cost and low pulse repetition frequency (PRF) poses a challenge in translating this technology to an affordable clinical imaging option at bed-side. Pulsed Laser Diodes (PLD) on the other hand is portable, inexpensive and offers high PRF.
View Article and Find Full Text PDFTo evaluate the clinical-phenotypic characteristics of Schmid metaphyseal chondrodysplasia (SMCD) inflicted by a novel missense mutation of COL10A1 gene: c.2020G > A; p.Gly674Arg.
View Article and Find Full Text PDFWe assessed the extent to which chemotherapy cycles recorded in Hospital Episode Statistics (HES) Admitted Patient Care (APC) were captured in National Cancer Registration & Analysis Service Systemic Anti-Cancer Therapy (SACT) for a cohort of lung cancer patients. All chemotherapy cycles recorded for linkage eligible lung cancer patients with a National Cancer Registration & Analysis Service diagnosis between 2012 and 2015 were identified in HES APC and SACT. Among a population of 4070 lung cancer patients, 6076 chemotherapy cycles were observed in HES APC data.
View Article and Find Full Text PDFProbiotics, prebiotics, and synbiotics are potential mediators to maintaining healthy intestinal flora and have garnered an area of wide research in the past few years. The current study assesses the in vivo effects of probiotic ( MBTU-HK1), prebiotic (acacia gum) (either singly or in combination as a synbiotic on growth performance), biochemical, hematological, physiological, and immunological effects and their role in the reduction of procarcinogen enzyme activities in male Balb/c mice. The absence of treatment-related toxicity and a normal physiological range of biochemical and hematological parameters ensure their safe consumption.
View Article and Find Full Text PDFA multidisciplinary approach is needed for the management of pregnancy related issues in women affected by Multiple Sclerosis, however little attention has been devoted to the modality of delivery. Here we aimed to investigate whether the diagnosis of multiple sclerosis (MS) influences delivery modality in MS patients. Patients who received the diagnosis before pregnancy showed a lower frequency of natural delivery and a higher frequency of both planned and urgency caesarean sections.
View Article and Find Full Text PDFBiomimetics (Basel)
November 2019
The rise of robots and robotics has proved to be a benefaction to humankind in different aspects. Robotics evolved from a simple button, has seen massive development over the years. Consequently, it has become an integral part of human life as robots are used for a wide range of applications ranging from indoor uses to interplanetary missions.
View Article and Find Full Text PDF