Publications by authors named "Santosh Tetali"
Article Synopsis
- Polyhydroxyalkanoates (PHAs) are biopolymers created by microorganisms when nutrients are limited, and they are considered a sustainable alternative to conventional plastics but face high production costs.
- This study focused on producing poly(3-hydroxybutyrate) (P(3HB)), a type of PHA, using the cyanobacterium Synechocystis sp. PCC6803 and tested various carbon sources and salinity levels for optimal production conditions.
- Despite achieving good lab results with acetate, lower P(3HB) production was seen in a larger outdoor photobioreactor, leading to the development of a new extraction method to remove pigments and confirming the biopolymer's suitability for
In the last few decades Additive Manufacturing has advanced and is becoming important for biomedical applications. In this study we look at a variety of biomedical devices including, bone implants, tooth implants, osteochondral tissue repair patches, general tissue repair patches, nerve guidance conduits (NGCs) and coronary artery stents to which fused deposition modelling (FDM) can be applied. We have proposed CAD designs for these devices and employed a cost-effective 3D printer to fabricate proof-of-concept prototypes.
View Article and Find Full Text PDFPolyhydroxyalkanoates (PHAs) are sustainable, versatile, biocompatible, and bioresorbable polymers that are suitable for biomedical applications. Produced via bacterial fermentation under nutrient-limiting conditions, they are uncovering a new horizon for devices in biomedical applications. A wide range of cell types including bone, cartilage, nerve, cardiac, and pancreatic cells, readily attach grow and are functional on PHAs.
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