Publications by authors named "Santosh Patel"

The scholarly academic productivity and publication activities of anesthesia departments within the United Arab Emirates (UAE) are currently unknown. We undertook a bibliometric study to quantify UAE anesthetists' contributions to various categories of articles in peer-reviewed high-impact anesthesia journals. Using a PubMed-based analysis, we studied the contribution of United Arab Emirates (UAE) anesthetists towards publications in eight high-impact anesthesia journals (represented in the database for 2023 from Journal Citation Reports®, Thomson Scientific) and four anesthesia subspecialty journals over five years ranging from 2019 to 2023.

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Article Synopsis
  • Bovicola caprae, an ectoparasite affecting goats globally, was studied in India to confirm its molecular characteristics and analyze its genetic diversity.
  • The study identified two distinct lineages of B. caprae, with Indian sequences clustering with archived sequences from China and Iran.
  • Results showed low nucleotide diversity but high haplotype diversity, indicating recent population expansion, along with significant genetic differentiation and limited gene flow among populations.
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Intravenous (IV) medication administration error remains a major concern during the perioperative period. This review examines inadvertent IV anaesthesia induction agent administration via high-risk routes. Using Medline and Google Scholar, the author searched published reports of inadvertent administration via neuraxial (intrathecal, epidural), peripheral nerve or plexus or intracerebroventricular (ICV) route.

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Therapeutic use of tranexamic acid (TXA) to minimise blood loss is common during a wide range of surgical procedures. This review aims to explore the clinical features of the accidental intrathecal administration of TXA and to identify contributory factors that might prevent future incidents. The author searched published reports of accidental intrathecal administration of TXA using Medline and Google Scholar databases from July 2018 to September 2022, including error reports in any language but excluding errors via nonintrathecal routes.

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People who use or sell drugs develop their own in-group terms and language, much like any other group of people with a common experience. Slang terms are derived from a wide variety of sources. These might include the physical appearance and/or type of drug, the place where it originates, the effect it has on users, or how it is packaged for sale.

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  • The review examines inadvertent cardiovascular medication errors during neuraxial procedures over the past 50 years, focusing on their prevalence, harm, and clinical consequences.
  • It highlights that these errors often involve drugs like digoxin and ephedrine, with many resulting in serious health issues, including permanent neurological deficits in some patients.
  • The analysis identifies key contributing factors to these errors, such as inadequate training for junior doctors and poor organizational practices, and recommends targeted safety strategies to prevent future incidents.
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Background: Administration of the wrong drug via the epidural or intrathecal route can cause devastating consequences. Because of the commonality of potassium replacement therapy coupled to its potential neurotoxic profile, we suspected that injuries related to this drug error would be present in the literature.

Objectives: We aimed to identify clinical characteristics associated with the inadvertent administration of potassium chloride (KCl) during neuraxial anesthesia.

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When developing treatment plans, the optimal approach is to address a patient's illness from multiple directions. Having a psychiatrist as part of the care team allows comprehensive assessment and treatment of behavioral, cognitive, and emotional domains to reduce social/occupational impairment, improve quality of life, and mitigate treatment nonadherence.

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Background: Drug errors during neuraxial anaesthesia or analgesia are not well known.

Objectives: To review the clinical consequences associated with incorrect administration of neuromuscular blocking drugs (NMBDs) during spinal or epidural anaesthesia, and to investigate human factors and strategies available to help prevent such errors.

Design: A review of reports of neuraxial administration of NMBDs in humans.

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Purpose: Sickle cell disease (SCD) is the most common and serious form of an inherited blood disorder that lead to higher risk of early mortality. SCD patients are at high risk for developing multiorgan acute and chronic complications linked with significant morbidity and mortality. Some of the ophthalmological complications of SCD include retinal changes, refractive errors, vitreous hemorrhage, and abnormalities of the cornea.

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Background: Drug administration errors in obstetric neuraxial anesthesia can have devastating consequences. Although fully recognizing that they represent "only the tip of the iceberg," published case reports/series of these errors were reviewed in detail with the aim of estimating the frequency and the nature of these errors.

Methods: We identified case reports and case series from MEDLINE and performed a quantitative analysis of the involved drugs, error setting, source of error, the observed complications, and any therapeutic interventions.

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Colorectal surgery carries significant morbidity and mortality, which is associated with an enormous use of healthcare resources. Patients with pre-existing morbidities, and those undergoing emergency colorectal surgery due to complications such as perforation, obstruction, or ischemia / infarction are at an increased risk for adverse outcomes. Fluid therapy in emergency colorectal surgical patients can be challenging as hypovolemic and septic shock may coexist.

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The regulator of G-protein signaling 5 (RGS5) belongs to a family of GTPase activators that terminate signaling cascades initiated by extracellular mediators and G-protein-coupled receptors. RGS5 has an interesting dual biological role. One functional RGS5 role is as a pericyte biomarker influencing the switch to angiogenesis during malignant progression.

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Colorectal surgery is commonly performed for colorectal cancer and other pathology such as diverticular and inflammatory bowel disease. Despite significant advances, such as laparoscopic techniques and multidisciplinary recovery programs, morbidity and mortality remain high and vary among surgical centers. The use of scoring systems and assessment of functional capacity may help in identifying high-risk patients and predicting complications.

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Various physiological mechanisms regulate sodium and water balance in the human body. These processes achieve acute and chronic sodium regulation and the simultaneous or sequential changes can be explained using a single physiological model. Steady intracellular water and osmolality is necessary for cell membrane integrity and cellular processes.

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Electrocardiographic (ECG) artifacts occur with the use of internal or external monitoring and therapeutic devices. Other common cause of ECG artifact is patient's motion. Electrocardiographic artifact during electroconvulsive therapy is not reported in the literature.

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Calotropis procera produces copious amounts of latex, which has been shown to possess several pharmacological properities. Its local application produces intense inflammatory response. In the 10 cases of Calotropis procera -induced keratitis reported here, the clinical picture showed corneal edema with striate keratopathy without any evidence of intraocular inflammation.

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