Publications by authors named "Santosh K"

Article Synopsis
  • Acute kidney injury (AKI) is common in patients with ST-elevation myocardial infarction and cardiogenic shock, particularly in low- and middle-income countries, showing a higher incidence compared to developed nations.
  • A study conducted in North India from 2016 to 2022 revealed that 45.5% of patients with this condition developed AKI, with several clinical factors (like heart failure and non-revascularization) identified as predictors.
  • AKI was found to significantly increase the risk of in-hospital mortality, indicating a need for further research on prevention and management strategies in resource-limited settings.
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Evaluation and comparison of natural products like triphala, eucalyptus and carvacol with conventional root canal irrigant such as sodium hypochlorite (NaOCL) and Chlorhexidine against persistent root canal pathogens like is of interest. Samples were taken both before irrigation as well as after irrigation. CFU was counted after the plates had been incubated overnight at temperature of 37°C overnight.

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Meta-learning empowers learning systems with the ability to acquire knowledge from multiple tasks, enabling faster adaptation and generalization to new tasks. This review provides a comprehensive technical overview of meta-learning, emphasizing its importance in real-world applications where data may be scarce or expensive to obtain. The article covers the state-of-the-art meta-learning approaches and explores the relationship between meta-learning and multi-task learning, transfer learning, domain adaptation and generalization, self-supervised learning, personalized federated learning, and continual learning.

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The emergence of the COVID-19 pandemic in Wuhan in 2019 led to the discovery of a novel coronavirus. The World Health Organization (WHO) designated it as a global pandemic on 11 March 2020 due to its rapid and widespread transmission. Its impact has had profound implications, particularly in the realm of public health.

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Human γδ T cells are highly enriched in epithelial cell-dominated compartments like skin. Nonetheless, their function in the pathogenesis of pemphigus vulgaris (PV), an autoimmune skin disorder, is lacking. Therefore, we investigated the functional expression of human γδT cell subsets along with their homing chemokine receptor-ligand and inflammatory cytokines in the immunopathogenesis of PV.

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Infertility has massively disrupted social and marital life, resulting in stressful emotional well-being. Early diagnosis is the utmost need for faster adaption to respond to these changes, which makes possible via AI tools. Our main objective is to comprehend the role of AI in fertility detection since we have primarily worked to find biomarkers and related risk factors associated with infertility.

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Background: COVID-19 can cause severe pneumonia that can progress to multiple organ failure. It is believed that dysregulation of inflammation and cytokine storm, contributes to severe COVID-19. As inflammatory mediators play an important role in the pathogenesis of the severe disease, inflammatory markers like fever, leucocytosis, and C-reactive protein are known to predict severe disease.

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Infertility is a social stigma for individuals, and male factors cause approximately 30% of infertility. Despite this, male infertility is underrecognized and underrepresented as a disease. According to the World Health Organization (WHO), changes in lifestyle and environmental factors are the prime reasons for the declining rate of male fertility.

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Machine learning is an effective and accurate technique to diagnose COVID-19 infections using image data, and chest X-Ray (CXR) is no exception. Considering privacy issues, machine learning scientists end up receiving less medical imaging data. Federated Learning (FL) is a privacy-preserving distributed machine learning paradigm that generates an unbiased global model that follows local model (from clients) without exposing their personal data.

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The presence of non-biomedical foreign objects (NBFO), such as coins, buttons and jewelry, and biomedical foreign objects (BFO), such as medical tubes and devices in chest X-rays (CXRs), make accurate interpretation difficult, as they do not indicate known biological abnormalities like excess fluids, tuberculosis (TB) or cysts. Such foreign objects need to be detected, localized, categorized as either NBFO or BFO, and removed from CXR or highlighted in CXR for effective abnormality analysis. Very specifically, NBFOs can adversely impact the process, as typical machine learning algorithms would consider these objects to be biological abnormalities producing false-positive cases.

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Chest X-ray (CXR) imaging is a low-cost, easy-to-use imaging alternative that can be used to diagnose/screen pulmonary abnormalities due to infectious diseaseX: Covid-19, Pneumonia and Tuberculosis (TB). Not limited to binary decisions (with respect to healthy cases) that are reported in the state-of-the-art literature, we also consider non-healthy CXR screening using a lightweight deep neural network (DNN) with a reduced number of epochs and parameters. On three diverse publicly accessible and fully categorized datasets, for non-healthy versus healthy CXR screening, the proposed DNN produced the following accuracies: 99.

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There has been an explosive growth in research over the last decade exploring machine learning techniques for analyzing chest X-ray (CXR) images for screening cardiopulmonary abnormalities. In particular, we have observed a strong interest in screening for tuberculosis (TB). This interest has coincided with the spectacular advances in deep learning (DL) that is primarily based on convolutional neural networks (CNNs).

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For COVID-19, the need for robust, inexpensive, and accessible screening becomes critical. Even though symptoms present differently, cough is still taken as one of the primary symptoms in severe and non-severe infections alike. For mass screening in resource-constrained regions, artificial intelligence (AI)-guided tools have progressively contributed to detect/screen COVID-19 infections using cough sounds.

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Starting from December 2019, the novel COVID-19 threatens human lives and economies across the world. It was a matter of grave concern for the governments of all the countries as the deadly virus started expanding its paws over neighboring regions of infected areas. The spread got uncontrollable, thereby leaving no choice for the nations but to impose and observe nationwide lockdown.

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The use of digital medical images is increasing with advanced computational power that has immensely contributed to developing more sophisticated machine learning techniques. Determination of age and gender of individuals was manually performed by forensic experts by their professional skills, which may take a few days to generate results. A fully automated system was developed that identifies the gender of humans and age based on digital images of teeth.

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Objective: Even with the immense progress achieved in the field of percutaneous coronary interventions (PCIs), treatment of diffuse long atherosclerotic coronary artery disease continues to remain a challenge for durable outcomes. The downstream reduction in diameter along the lesion length of a coronary artery may compel the cardiologist to use either 2 overlapping stents of different diameters or a single long stent leading to stent-vessel mismatch at the edges. Recently, Meril Life Sciences Pvt.

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Since December 2019, the novel COVID-19's spread rate is exponential, and AI-driven tools are used to prevent further spreading [1]. They can help predict, screen, and diagnose COVID-19 positive cases. Within this scope, imaging with Computed Tomography (CT) scans and Chest X-rays (CXRs) are widely used in mass triage situations.

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Gait abnormalities and cognitive dysfunction are common in patients with Parkinson's disease (PD) and get worse with disease progression. Recent evidence has suggested a strong relationship between gait abnormalities and cognitive dysfunction in PD patients and impaired cognitive control could be one of the causes for abnormal gait patterns. However, the pathophysiological mechanisms of cognitive dysfunction in PD patients with gait problems are unclear.

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In this paper, considering year 2020 and Covid-19, we analyze medical imaging tools and their performance scores in accordance with the dataset size and their complexity. For this, we mainly consider AI-driven tools that employ two different types of image data, namely chest Computed Tomography (CT) and X-ray. We elaborate on their strengths and weaknesses by taking the following important factors into account: i) dataset size; ii) model fitting criteria (over-fitting and under-fitting); iii) transfer learning in the deep learning era; and iv) data augmentation.

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Automated assessment and segmentation of Brain MRI images facilitate towards detection of neurological diseases and disorders. In this paper, we propose an improved U-Net with VGG-16 to segment Brain MRI images and identify region-of-interest (tumor cells). We compare results of improved U-Net with a custom-designed U-Net architecture by analyzing the TCGA-LGG dataset (3929 images) from the TCI archive, and achieve pixel accuracies of 0.

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Background: Cannabis is one of the most used illicit substances in India but is under-recognized and under-represented in clinical settings of India, especially at primary care. Patients usually do not seek treatment primarily for cannabis use, but it is identified on pro-active questioning by doctors. The aim is to study the clinical profiles of patients with cannabis use disorders (CUD) at primary care and to derive learning points from collaborative consultations to devise an optional module for CUD primarily for primary care doctors (PCDs).

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