Publications by authors named "Santosh Bastola"

Hypoglycemic encephalopathy is a rare yet life-threatening diabetes complication, where overlapping symptoms with neurological conditions can delay diagnosis. Early recognition and treatment are crucial to prevent irreversible brain damage. Clinicians should suspect hypoglycemia in diabetic patients with altered mental status, as timely intervention improves outcomes and reduces mortality.

View Article and Find Full Text PDF

Background: The present study aimed to quantify the burden of structural heart disease in Nepali children.

Methods: We performed a school-based cross-sectional echocardiographic screening study with cluster random sampling among children 5-16 years of age.

Results: Between December 2012 and January 2019, 6573 children (mean age 10.

View Article and Find Full Text PDF

Importance: Echocardiographic screening allows for early detection of subclinical stages of rheumatic heart disease among children in endemic regions.

Objective: To investigate the effectiveness of systematic echocardiographic screening in combination with secondary antibiotic prophylaxis on the prevalence of rheumatic heart disease.

Design, Setting, And Participants: This cluster randomized clinical trial included students 9 to 16 years of age attending public and private schools in urban and rural areas of the Sunsari district in Nepal that had been randomly selected on November 17, 2012.

View Article and Find Full Text PDF

Background: With an ageing global population comes major non-communicable disease burden, especially in low-income and middle-income countries. An unknown proportion of this burden is treatable or palliated with surgery. This study aimed to estimate the surgical needs of individuals aged 50 years or older in Nepal.

View Article and Find Full Text PDF

Background: With an aging global population comes an obligate and substantial burden of noncommunicable disease, especially in low- and middle-income countries. An unknown proportion of this burden is treatable with surgical expertise. For health system planning, this study aimed to estimate the operative needs of individuals older than 50 of age years in Nepal.

View Article and Find Full Text PDF