Incidence and risk factors of acute kidney injury in redo cardiac surgery: a single center analysis.

The incidence, risk factors and prognostic implications of acute kidney injury (AKI) in patients undergoing redo cardiac surgery are still poorly defined. We prospectively collected data on 394 consecutive redo patients between January 2011 and October 2020. Patients were divided into groups according to the occurrence of different degrees of postoperative AKI (No AKI vs.

Visits to Health Centers Among Adults, by Selected Characteristics: United States, 2022.

Objective: This report describes care received at health centers in the United States in 2022. Estimates are presented for selected characteristics.

Methods: The data presented in this report are from the 2022 National Ambulatory Medical Care Survey Health Center Component.

Compression Molding of Low-Density Polyethylene Matrix/Glass-Fiber-Reinforced Thick Laminates.

Thermoplastic fiberglass was compression molded in the form of thick panels with a nominal thickness of 10 mm and a size of 300 × 300 mm. A simplified procedure was adopted to speed up the lamination procedure and adapt it to the aim of recycling waste, glass fibers, fabrics, and thermoplastic films. Low density polyethylene was used as a matrix to simplify the laboratory process, but the same procedure can be extended to other thermoplastic film, such as polyamide.

Four-year effectiveness, safety and drug retention rate of secukinumab in psoriatic arthritis: a real-life Italian multicenter cohort.

Objectives: to evaluate over a 48-month follow-up period the: 1) long-term effectiveness and safety; 2) drug retention rate (DRR); 3) impact of comorbidities and bDMARDs line on MDA and DAPSA remission/low disease activity (LDA) of secukinumab in a multicenter Italian cohort of PsA patients.

Methods: Consecutive PsA patients receiving secukinumab were followed prospectively in Italian centers between 2016 and 2023. Disease characteristics, previous/ongoing treatments, comorbidities and follow-up duration were recorded.

Four-year real-world experience of secukinumab in a large Italian cohort of axial spondyloarthritis.

Objectives: This study aims to evaluate in a real-life Italian multicenter cohort of axial spondyloarthritis (axSpA) (1) the 4-year effectiveness and safety of secukinumab, (2) the drug retention rate (DRR), and (3) the impact of the line of bDMARDs treatment, subtype of axSpA, and sex on achieving low disease activity (LDA) and very low disease activity (VLDA).

Methods: Consecutive axSpA patients receiving secukinumab between 2016 and 2023 were prospectively evaluated. Data on disease characteristics, previous/ongoing treatments, comorbidities, and follow-up duration were collected.

Emergency Department Visits by Homeless Status and Sex: United States, 2016-2021.

Objectives-This report describes emergency department (ED) visits by homeless status and sex. Methods-Nationally representative estimates were calculated from data collected in the 2016-2021 National Hospital Ambulatory Medical Care Survey, an annual national probability sample survey of ED visits in the United States. Visits by people experiencing homelessness were defined using data on patient residence from medical records.

Comparison of the precursor, amino acid oxidation, and end-product methods for the evaluation of protein turnover in senior dogs.

Stable isotope methods have been used to study protein metabolism in humans; however, there application in dogs has not been frequently explored. The present study compared the methods of precursor (13C-Leucine), end-products (15N-Glycine), and amino acid oxidation (13C-Phenylalanine) to determine the whole-body protein turnover rate in senior dogs. Six dogs (12.

Tissue factor pathway-related biomarkers in liver cancer: activated factor VII-antithrombin complex and tissue factor mRNA levels are associated with mortality.

Background: Tissue factor (TF), the main initiator of the coagulation cascade, plays a role in cancer progression and prognosis. Activated factor VII-antithrombin complex (FVIIa-AT) is considered an indirect marker of TF exposure by reflecting TF-FVIIa interaction.

Objectives: To assess the link between FVIIa-AT plasma levels, messenger RNA (mRNA) expression, and survival in cancer.

Trends in Emergency Department Visits Among People Younger Than Age 65 by Insurance Status: United States, 2010-2021.

Purpose-This report describes trends in emergency department visits among people younger than age 65 from 2010 through 2021, by health insurance status and selected demographic and hospital characteristics. Methods-Estimates in this report are based on data collected in the 2010-2021 National Hospital Ambulatory Medical Care Survey. Data were weighted to produce annual national estimates.

Emergency Department Visit Rates by Adults With Diabetes: United States, 2020-2021.

In 2021, diabetes was the eighth leading cause of death in the United States (1). Over 37 million Americans have diabetes (2). While it most often develops in people older than age 45 (3), its frequency is increasing in young adults (4).

Temporal Variation in Introgressed Segments' Length Statistics Computed from a Limited Number of Ancient Genomes Sheds Light on Past Admixture Pulses.

Hybridization is recognized as an important evolutionary force, but identifying and timing admixture events between divergent lineages remain a major aim of evolutionary biology. While this has traditionally been done using inferential tools on contemporary genomes, the latest advances in paleogenomics have provided a growing wealth of temporally distributed genomic data. Here, we used individual-based simulations to generate chromosome-level genomic data for a 2-population system and described temporal neutral introgression patterns under a single- and 2-pulse admixture model.

Emergency Department Visit Rates for Assault: United States, 2019-2021.

Nonfatal injuries are major causes of emergency department (ED) visits in the United States (1). The National Center for Injury Prevention and Control estimated that, in 2020, 22.9 million ED visits related to nonfatal injuries occurred (1).

Mandibular reconstruction with TMJ prosthesis: management of osteomyelitis after orthognathic surgery (Case Report).

This case report presents a mandible reconstruction with temporomandibular joint (TMJ) prothesis for treatment of osteomyelitis infection following a bimaxillary orthognathic and genioplasty surgeries. The patient, a 41-year-old female, presented with facial pain, difficulty in opening her mouth, and mandibular deviation four months after the initial orthognathic surgery. During the four months, the patient had experienced two more surgerys post-operative for treatment of the complications.

Comorbidities in the Spondyloarthritis GISEA Cohort: an average treatment effect analysis on patients treated with bDMARDs.

Objectives: We aimed to investigate the effectiveness of tumour necrosis factor inhibitors (TNFi), anti-interleukin-17 or interleukin-12/23 monoclonal antibodies (anti-IL) on comorbidities in a cohort of patients with spondyloarthritis (SpA), using an average treatment effect (ATE) analysis.

Methods: SpA patients from the multicentre Italian GISEA Registry were divided into groups according to pharmacological exposure: no treatment (G0), TNFi (G1) and non-responders to TNFi switched to anti-IL (G2). In each group, we recorded the prevalence and incidence of infectious, cardiopulmonary, endocrinological, gastrointestinal, oncologic, renal and neurologic comorbidities.

Streamlined Strategy for Scalable and Enantioselective Total Syntheses of the Eburnane Alkaloids.

A general, concise, and efficient strategy for the enantioselective synthesis of the eburnane alkaloid family of natural products is disclosed. Specifically, 13 members of the natural product family were prepared from commercially available and inexpensive starting materials. The brevity and modularity of the route are largely on account of a two-phase synthesis logic and a key catalytic enantioconvergent cross-coupling to establish the C20 stereogenic center.

High Prevalence of Kidney Stone Disease of Gouty Origin in Roman Pontiffs Reigning in the Years 537-2005.

Objectives: Many Roman pontiffs are known to have had kidney stone disease. However, no specific report has explored the prevalence of the various stones in popes, which is the purpose of this study.

Materials And Methods: We extensively studied the histories of all popes (n = 264) from Saint Peter to John Paul II (34-2005).

Acute Kidney Injury as a Leading Cause of Papal Deaths in the Years 1277 to 2005: A Review of 21 Cases.

Objectives: This study was devised to investigate papal deaths due to acute kidney injury, a topic for which scarce data exist.

Materials And Methods: We studied all popes between John XXI, who died in 1277 of crush syndrome, and John Paul II, who died of anuria and urinary sepsis in 2005.

Results: Between pontification years from 1277 to 2005, 21 of 78 popes (26.

Malaria as a Papal Disease.

Objectives: In this study, we aimed to investigate the effects of malaria on the lives of Roman pontiffs.

Materials And Methods: The histories of all 264 popes from Saint Peter to John Paul II were extensively studied.

Results: Malaria affected the lives of Roman pontiffs.