Publications by authors named "Santip Kongjorn"
Full genome-based characterization of G4P[6] rotavirus strains from diarrheic patients in Thailand: Evidence for independent porcine-to-human interspecies transmission events.
Ratana Tacharoenmuang Ratigorn Guntapong Sompong Upachai Phakapun Singchai Saori Fukuda Santip Kongjorn
Virus Genes
August 2021
Article Synopsis
- The evolutionary patterns of G4P[6] rotavirus strains in humans are still unclear, particularly regarding their modes of transmission (animal to human vs. human to human).
- Two specific G4P[6] strains were identified in Thailand from patients with severe diarrhea, showing unique genetic characteristics and similarities to porcine rotavirus strains.
- Genetic and phylogenetic analyses reveal that these strains likely originated from independent transmissions between pigs and humans, which highlights the interactions and exchanges between rotavirus strains across species.
An unusual rotavirus strain with the G3P[10] genotype (RVA/Human-wt/THA/MS2015-1-0001/2015/G3P[10]) was identified in a stool sample from a hospitalized child aged 11 months with severe gastroenteritis in Thailand. In the current study, we sequenced and characterized the full genome of strain MS2015-1-0001. On full-genomic analysis, strain MS2015-1-0001 exhibited the following genotype configuration: G3-P[10]-I8-R3-C3-M3-A9-N3-T3-E3-H6, which is identical or closely related to those of bat and bat-like rotavirus strains (MYAS33-like).
View Article and Find Full Text PDFArticle Synopsis
- Recent reports have surfaced regarding the emergence of unusual DS-1-like intergenogroup reassortant rotaviruses with G1/3/8 genotypes across various continents including Africa, Asia, Australia, Europe, and the Americas.
- In Thailand, three novel strains (G9P[8] genotype) were discovered in stool samples from children with diarrhea, and their full genomes were analyzed.
- Phylogenetic analysis revealed that these strains are unique multiple reassortants, indicating their genetic relationship with both human and co-circulating rotavirus strains, marking the first documentation of these specific reassortant strains.