Publications by authors named "Santilna Karolina Sahadevan"
J Pharm Pharmacol
August 2019
Article Synopsis
- The study aimed to explore the effects of combining desferrioxamine (DFO) and dextromethorphan (DXM) on Parkinson's disease symptoms in a rat model.
- By inducing Parkinson's using 6-hydroxydopamine, researchers assessed changes in behavior and neurobiochemical markers, finding that the combination treatment significantly improved motor symptoms and antioxidant enzyme levels while reducing harmful substances in the brain.
- The findings suggest that DFO and DXM may work together to protect dopamine neurons and mitigate symptoms of Parkinson's by reducing excitotoxicity and inflammation, indicating a potential therapeutic strategy for managing the disease.
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