impairs mitochondrial function and metabolism during infection of corneal epithelial cells.

(PA) is a gram-negative opportunistic pathogen that can infect the cornea as a result of trauma or contact lens wear. In addition to their known energy producing role, mitochondria are important mediators of immune signaling and host defense. While certain pathogens have developed strategies to evade host defenses by modulating host mitochondrial dynamics and metabolism, the ability of PA to harness host cell mitochondria during corneal infection is unknown.

Sources and distribution of organic matter along the Ring of Cenotes, Yucatan, Mexico: sterol markers and statistical approaches.

The Yucatan Peninsula is a large low lying platform of limestone, dolomite and evaporite deposits, forming an extensive and mature karst aquifer with many sinkholes locally called cenotes. In Yucatan, the only source of drinking water is groundwater and its quality could be impaired by: (i) infiltration of contaminants and (ii) saltwater intrusion. To investigate the sources of organic matter in this aquifer, sediment samples (46) were collected from cenotes and analysed using gas chromatography-mass spectrometry.