Publications by authors named "Santiago Perez-Parra"

Article Synopsis
  • The study analyzes 88 SARS-CoV-2 genomes from COVID-19 patients at "Reina Sofía" Hospital in Spain between October 2020 and April 2021 to track emerging variants and mutations.
  • It notes that the 20E (EU1) variant was predominant at 71.6%, while the Alpha variant was rising at 14.8%, with concerning mutations found in the spike protein of some 20E genomes.
  • Statistical analysis indicates a significant correlation between the age of patients and the severity of COVID-19 symptoms, particularly in samples with more genetic mutations.
View Article and Find Full Text PDF

Kaposi´s sarcoma is a rare tumor associated with human herpes virus 8 (HHV-8) infection. Four main clinical subtypes have been described. This study reports on a form of KS in an HIV negative and immunocompetent middle-aged man.

View Article and Find Full Text PDF

Phylogenetic studies are a valuable tool to understand viral transmission patterns and the role of immigration in HIV-1 spread. We analyzed the spatio-temporal relationship of different HIV-1 non-B subtype variants over time using phylogenetic analysis techniques. We collected 693 pol (PR+RT) sequences that were sampled from 2005 to 2012 from naïve patients in different hospitals in southern Spain.

View Article and Find Full Text PDF

Background: Since 1982, HIV-1 epidemics have evolved to different scenarios in terms of transmission routes, subtype distribution and characteristics of transmission clusters. We investigated the evolutionary history of HIV-1 subtype B in south Spain.

Patients & Methods: We studied all newly diagnosed HIV-1 subtype B patients in East Andalusia during the 2005-2012 period.

View Article and Find Full Text PDF

We present a case report of a infective endocarditis by Corynebacterium pseudodiphtheriticum in a young patient eight years old with bicuspid aortic valve that led to a severe neurological embolism and death. Corynebacterium pseudodiphtheriticum is part of the nasopharyngeal and skin flora. However, there are cases reported of endocarditis usually associated with immunocompromised patients that mostly presented a poor clinical outcome.

View Article and Find Full Text PDF

Introduction And Objective: Protease and reverse transcriptase HIV-1 sequences provide useful information for patient clinical management, as well as information on resistance to antiretrovirals. The aim of this study is to evaluate transmission events, transmitted drug resistance, and to georeference subtypes among newly diagnosed patients referred to our center.

Methods: A study was conducted on 693 patients diagnosed between 2005 and 2012 in Southern Spain.

View Article and Find Full Text PDF

Majocchi's granuloma is a persistent supurative folliculitis, associated with a deep granulomatous reaction induced by dermatophytes. There are two clinical forms of Majocchi's granuloma: the superficial form that appears in healthy individuals after localized trauma; and the nodular form, which occurs in inmunocompromised patients. We present a case of nodular Majocchi's granuloma on the forearm of an immunocompetent patient.

View Article and Find Full Text PDF