Publications by authors named "Santiago Otero-Martinez"
We determined the serum concentration of biotin, zinc, antiepileptic drugs, and biotinidase enzyme activity in 20 children treated with valproic acid, in 10 children treated with carbamazepine, and in 75 age- and sex-matched healthy controls. There were no significant differences in the serum levels of biotin, and biotinidase enzyme activity between the patients treated with valproic acid, the patients treated with carbamazepine, and the control group. Zinc serum levels were lower in the patients treated with valproic acid and with carbamazepine than in the control group, but within the normal range.
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- Serum magnesium (Mg) levels are crucial for monitoring patient health and diagnosing diseases in clinical settings.
- A study in Spain revalidated colorimetric methods for measuring serum Mg according to ISO 15189 standards, using data from interlaboratory comparisons to assess quality.
- Results showed high precision and accuracy for most hospitals, highlighting a reliable revalidation process that can integrate smoothly into existing lab workflows without disrupting routine activities.