Publications by authors named "Santiago Nogue Xarau"

Objective: To present questions about poisoning to 4 artificial intelligence (AI) systems and 4 clinical toxicologists and determine whether readers can identify the source of the answers. To evaluate and compare text quality and level of knowledge found in the AI and toxicologists' responses.

Methods: Ten questions about toxicology were presented to the following AI systems: Copilot, Bard, Luzia, and ChatGPT.

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Objectives: To determine whether symptoms and levels of severity of intoxication from street drugs differ between adolescents and young adults who come to hospital emergency departments for treatment.

Material And Methods: We studied a consecutive cohort of adolescents (aged 12-17 years) and young adults (aged 18-30 years) who were treated in 11 hospital emergency departments belonging to the Drug Abuse Network of Spanish Hospital Emergency Departments (REDURHE). Sociodemographic and clinical characteristics and level of severity were recorded for comparison between between adolescents and young adults, adjusted for sex, alcohol co-ingestion, and type of drug used.

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Objectives: To identify the most common problems related to use of N-acetylcysteine to reverse the toxic effects of paracetamol poisoning.

Material And Methods: Retrospective descriptive observational study of clinical records for patients treated for paracetamol poisoning in 4 emergency departments during 3 years (2017-2019). We analyzed epidemiologic, clinical, and care variables, especially those related to the suitability and safety of using N-acetylcysteine as an antidote.

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Article Synopsis
  • The study aimed to analyze the characteristics and severity of drug overdoses treated in Spanish hospital emergency departments, looking specifically at differences between weekdays and weekends/holidays.
  • Over a 24-month period, 4526 patients were examined, with the most common drugs being cocaine, cannabis, and amphetamines; the majority of patients were male and around 33 years old.
  • Significant findings included younger patients presenting on weekends, a higher occurrence of alcohol use with drugs during this time, and fewer opioid emergencies compared to weekdays.
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We have read with great interest the article by Lionte et al., "Association of multiple glycemic parameters at hospital admission with mortality and short-term outcomes in acutely poisoned patients", recently published in your journal [..

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Objectives: Activated charcoal in suspension contains 600 mg/mL of sucrose. We aimed to assess the impact of an activated charcoal suspension on blood glucose levels in patients with acute medication poisoning.

Material And Methods: We identified drug patients whose blood glucose levels were measured before and after administration of activated charcoal to treat poisoning.

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Objective: To prepare a list of highly toxic drugs in infants (HTDs) marketed in Spain, comparing those that reach the lethal dose in a child of 10kg with the ingestion of 1 to 3 units.

Method: HTDs are defined as those capable of causing severe or lethal poisoning in children less than 8-year-old. Severe poisoning is considered as that corresponding to Grade 3 in the Poisoning Severity Score classification and to the "major effects" category in publications in the American Association of Poison Control Centers.

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Objective: There are few epidemiological studies on acute poisonings from pesticides, industrials and household products in Spain. The objective of this work is to describe the epidemiological and clinical profile of acute poisonings by chemical products in our country, and analyze their annual evolution.

Methods: The Spanish Toxicovigilance System (SETv) is a prospective registry that includes 32 Emergency Departments and Intensive Care Units in Spain.

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Objectives: To study the epidemiology of emergency department visits for transient global amnesia (TGA) by itself or associated with substance abuse or sexual assault.

Material And Methods: Retrospective study of cases treated from January to December 2018. Data for all patients with TGA were extracted, and cases were classified as associated with substance abuse (TGASUB), sexual assault (TGASEX), or neither (TGAONLY).

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Objective: To describe the characteristics of paediatric patients with suspected poisoning treated by advanced life support (ALS) units, and to evaluate quality indicators (QI) for the prehospital emergency care of these patients.

Method: A one-year observational study of patients under 18 years of age exposed to poisoning and treated by an ALS unit of the Medical Emergency System in Catalonia. Severe clinical criteria were defined, with 8 QI being evaluated for prehospital emergency care of poisoned paediatric patients.

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Objectives: Digoxin poisoning is a frequent reason for seeking emergency care. This study aimed to assess mortality related to digoxin poisoning.

Material And Methods: Descriptive observational study of digoxin poisonings attended in the emergency departments of 4 hospitals in Catalonia from 2013 through 2015.

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Emergencies due to snakebites, although unusual in Spain, are potentially serious. Of the 13 species native to the Iberian peninsula, only 5 are poisonous: 2 belong to the Colubridae family and 3 to the Viperidae family. Bites from these venemous snakes can be life-threatening, but the venomous species can be easily identified by attending to certain physical traits.

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Background And Objective: Antidotes may have a relevant role in acute intoxication management and the time until its administration can influence patient survival.

Patients And Method: Study conducted by a questionnaire sent in early 2015 to 70 hospitals in Catalonia providing emergency services. Qualitative availability on each antidote was considered adequate when present in at least 80% of hospitals.

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