Publications by authors named "Santiago Leandro Escobar-Davila"
Article Synopsis
- Vasculitides are disorders that can impact multiple organs both in the short and long term, often linked to various causes like cancer-related syndromes and medications.
- Cancer treatments, especially those targeting HER2, can lead to complications such as skin and lung vasculitis.
- This text highlights a unique case of Henoch-Schönlein purpura occurring in a patient with HER2 breast cancer treated with T-DM1.
We present the case of a 64-year-old female with stage IV gastric adenocarcinoma, pulmonary, and abdominal wall metastases, and no history of cardiovascular disease. In palliative care, she received systemic cytotoxic treatment with fluorouracil, leucovorin, oxaliplatin, and docetaxel protocol, which was well tolerated over five cycles. During cycle 6, she presented with cardiovascular symptoms with hemodynamic consequences while receiving oxaliplatin injection without docetaxel or 5-fluorouracil.
View Article and Find Full Text PDFFirst case report of tumor lysis syndrome after third line systemic therapy with gemcitabine and pazopanib in a patient with lower extremity soft tissue sarcoma.
Edith Norela Benitez-Escobar Duvan Arley Galindes-Casanova Luis Álvaro Melo-Burbano Diana Marcela Bonilla-Bonilla Luis Miguel Osorio-Toro
Chin Clin Oncol
August 2023
Article Synopsis
- Tumor lysis syndrome (TLS) is a serious condition that can occur after cancer treatment, causing rapid tumor cell destruction and serious electrolyte imbalances, particularly in patients with blood cancers, but rarely in those with solid tumors like sarcomas.
- The case discusses a patient with high-grade sarcoma who experienced TLS after starting a new treatment regimen with gemcitabine and pazopanib, resulting in kidney issues and requiring hemodialysis.
- After receiving antibiotic treatment and some recovery, the patient continued the chemotherapy but ultimately died from respiratory complications eight months after discharge, highlighting the risks and challenges in treating advanced sarcoma.