Stem cell grafting for epilepsy: clinical promise and ethical concerns.

The recent explosion of research on stem cells and neural grafting holds great promise for many neurological conditions, including epilepsy. Potential roles for cell grafting in epilepsy include remodeling of dysfunctional neuronal circuits and local delivery of neuromodulatory or neuroprotective factors. While many basic questions remain to be answered, initial human trials are underway in epilepsy as well as Parkinson's disease, Alzheimer's disease, stroke, and other conditions.