Publications by authors named "Santiago Gimenez De Mestral"
Background: Myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML) are associated with cutaneous manifestations. Next-generation sequencing (NGS) is a tool capable of identifying clonal myeloid cells in the skin infiltrate and thus better characterize the link between hematological diseases and skin lesions.
Objective: To assess whether skin lesions of MDS/CMML are clonally related to blood or bone marrow cells using NGS.
Article Synopsis
- - A 26-year-old female was diagnosed with serrated polyposis syndrome after experiencing gastrointestinal symptoms, leading to further screening.
- - Screening revealed a serpiginous papilla, potentially dysplastic, and biopsies confirmed it as a serrated lesion.
- - This case marks the first link between duodenal serrated lesions and serrated polyposis syndrome, suggesting that upper GI screening may not be effective, but colonoscopy is recommended for patients with upper GI serrated lesions.