A cross-sectional epidemiological study conducted in Argentina to evaluate the impact of the exposome on skin aging.

Background: Skin aging is a gradual cumulative process that may be accelerated by various exposome factors.

Aims: To investigate associations between exposome factors and facial skin aging in 11 locations in Argentina.

Patients/methods: An observational, cross-sectional study with assessments by exposome questionnaire, Glogau photoaging classification from I to IV, AI-based algorithm analysis of 7 skin aging signs, and SCINEXA score.