Publications by authors named "Santiago Atehortua Munoz"
Article Synopsis
- * Diagnosis includes a range of tests using samples from cerebrospinal fluid, blood, and other sources, employing methods such as microscopy, cultures, and imaging techniques like MRI.
- * Treatment typically involves antimicrobial therapy for non-viral infections and supportive care, while this article specifically addresses acute central nervous system infections in patients beyond the neonatal stage, excluding certain infections and vaccines.
Biofire FilmArray Meningitis/Encephalitis panel for the aetiological diagnosis of central nervous system infections: A systematic review and diagnostic test accuracy meta-analysis.
Juliana Trujillo-Gómez Sofia Tsokani Catalina Arango-Ferreira Santiago Atehortúa-Muñoz Maria José Jimenez-Villegas
EClinicalMedicine
February 2022
Article Synopsis
- The study evaluates the diagnostic test accuracy (DTA) of the FilmArray Meningitis/Encephalitis (FA/ME) panel in patients suspected of having central nervous system infections, aiming to clarify its clinical benefits.* -
- A systematic review and meta-analysis was conducted, analyzing data from 19 studies involving over 11,000 participants, assessing the sensitivity and specificity of FA/ME compared to standard reference tests (like CSF/blood cultures and PCR).* -
- The findings suggest that FA/ME has high sensitivity (up to 92.1%) and specificity (up to 99.2%) for detecting bacterial and certain viral infections, although the reliability of the evidence remains low.*