Publications by authors named "Santhosh Kumar Kodagalli Nagaraju"
Pharmaceuticals (Basel)
May 2024
Article Synopsis
- - Managing chemotherapy-induced nausea and vomiting (CINV) in children is complicated due to variations in chemotherapy types, their emetic potential, and differences in how children process medications compared to adults.
- - Common anti-emetics for CINV in kids include dexamethasone, neurokinin-1 receptor antagonists, 5HT3 receptor antagonists, and olanzapine, with discrepancies in dosing and formulations leading to challenges, especially for younger children.
- - Newer agents like olanzapine show promise but come with potential side effects, while careful consideration of drug interactions—especially concerning safety risks like QTc prolongation—is essential in treatment planning.
