Combining Mesenchymal Stem Cells Derived from Wharton's Jelly and Amniotic Biomaterial Scaffolds for Cell Delivery.

Therapies based on mesenchymal stem cells have incredible potential for tissue regeneration. Tracking cells and keeping them at the injury site are creating challenges. The cells can be sown into a biocompatible scaffold as a possible remedy.

Synthesis and characterization of Hypsizygus ulmarius extract mediated silver nanoparticles (AgNPs) and test their potentiality on antimicrobial and anticancer effects.

The prime aim of this research is to discover new, eco-friendly approaches to reducing agents for manufacturing silver nanoparticles (AgNPs) from fresh fruiting bodies of the edible mushroom Hypsizygus ulmarius (Hu). The confirmation of Hu-mediated AgNPs has been characterized by UV visible spectroscopy, XRD, FTIR, SEM with EDX, HRTEM, AFM, PSA, Zeta poetical and GCMS analysis. The absorption peak of Hu-AgNPs at 430 nm has been confirmed by UV-visible spectroscopy analysis.

Transient downregulation of NR4A1 leads to impaired osteoblast differentiation through the TGF-ß pathway, and Elesclomol (STA-4783) rescues this phenotype.

Bone formation is regulated by numerous factors, such as transcription factors, cytokines, and extracellular matrix molecules. Human hormone nuclear receptors (hHNR) are a family of ligand-regulated transcription factors that are activated by steroid hormones, such as estrogen and progesterone, and various lipid-soluble signals, including retinoic acid, oxysterols, and thyroid hormone. We found that an hHNR called NR4A1 was the most highly expressed after human MSC differentiation into osteoblasts by whole-genome microarray.

Au integrated 2D ZnO heterostructures as robust visible light photocatalysts.

Integration of semiconducting nanostructures with noble metal nanoparticles are turning highly desirable for cost efficient energy and environmental related applications. From this viewpoint, we report on a facile aqueous synthesis of polymer capped gold (Au) nanoparticles on free standing 2D layered structures of zinc oxide (ZnO) to result with ZnO/Au nanocomposites. Concentration of Au nanoparticles were observed to promote the preferential growth of ZnO along the (002) wurtzite plane.

Surface dissolution and transesterification of thermoset dimethacrylate polymer by dimethacrylate adhesive resin and organic catalyst-alcohol solution.

Objectives: To evaluate transesterification based dissolution of dimethacrylate and epoxy polymers, the former containing ester groups. Polymer substrates were treated with an adhesive resin (Stick™ Resin) and an organic catalyst-alcohol solution (ethylene glycol and triazabicyclodecene). The surface was chemically and nanomechanically analyzed with Fourier Transform-Infrared (FTIR) spectroscopy, surface profile peak (R) and nanohardness and modulus of elasticity.

The effect of ethanol on surface of semi-interpenetrating polymer network (IPN) polymer matrix of glass-fibre reinforced composite.

Aim Of The Study: The aim of this laboratory study was to evaluate the effect of ethanol treatment on the surface roughness (S), nano-mechanical properties (NMP) and surface characterization of dental fiber reinforced composite (FRC) with semi-interpenetrating polymer network (IPN).

Materials And Methods: A total of 240 FRC specimens with bisphenol A-glycidyl methacrylate - triethyleneglycol dimethacrylate - Poly (methylmetahcrylate) (bis-GMA-TEGDMA-PMMA) IPN matrix system were light cured for 40 s and divided into 2 groups (L and LH). The group LH was further post-cured by heat at 95 °C for 25 min.

Effect of ethanol treatment on mechanical properties of heat-polymerized polymethyl methacrylate denture base polymer.

This laboratory study was assessing the nano-mechanical properties (NMP), surface roughness (S), and topographic changes caused by ethanol on the surface of heat-polymerized denture base polymers at different time past dough stage. Specimens of heat polymerizing acrylic resin (Interacryl Hot, Interdent, Celje, Slovenia) of size 10×10×3 mm were prepared, wet ground, and polished for uniform smoothness and treated with ethanol in concentrations of 40, 70, and 99.9% for 30, 60, and 120 s and statistical analysis was done.

Effect of smoking on the genetic makeup of toll-like receptors 2 and 6.

Background: Cigarette smoking is a major risk factor for lung cancer, asthma, and oral cancer, and is central to the altered innate immune responsiveness to infection. Many hypotheses have provided evidence that cigarette smoking induces more genetic changes in genes involved in the development of many cigarette-related diseases. This alteration may be from single-nucleotide polymorphisms (SNPs) in innate immunity genes, especially the toll-like receptors (TLRs).

Photoactivated disinfection (PAD) of dental root canal system - An ex-vivo study.

Aim: To investigate the efficacy of photo activated disinfection (PAD) in reducing colony-forming unit (CFU) counts of Enterococcus faecalis (E. faecalis) in infected dental root canals. The study compared the efficacy of PAD with conventional endodontic treatment (CET) and also a combination of CET along with PAD.

Outcome of Palliative and Radical Radiotherapy in Patients with Oral Squamous Cell Carcinoma - a Retrospective Study.

Background: The treatment selection for the oral squamous cell carcinoma remains controversial. Radiation therapy or surgical excision of the lesion can be applied as the sole treatment or it can be used in combination with other treatment modalities. Radiotherapy is considered to be the safest of all the treatment modalities and can be used in several situations for oral and oropharyngeal cancers.

Effect of solvent/disinfectant ethanol on the micro-surface structure and properties of multiphase denture base polymers.

Aim Of The Study: The aim of this study was to evaluate the effect of solvent/disinfectant ethanol on the surface of denture base polymers. Changes in surface roughness, topography and some nanomechanical properties were assessed by SEM and nanoindentation plotted against different concentrations of ethanol on heat cured and autopolymerized polymetyl methacrylate based acrylic denture base polymers.

Materials And Methods: Test specimens (10×10×3mm(3)) of heat-curing (HC) and auto-polymerizing (AP) acrylic resin were prepared and polished to obtain uniform smoothness which were further grouped into 3 sub-groups HC1, HC2, HC3 and AP1, AP2, AP3 respectively 10 specimens (n) in each group.