Publications by authors named "Santhiya Vijayakumar"
is a highly infectious and antibiotic-resistant bacterium, which causes acute and chronic nosocomial infections. exhibits multidrug resistance due to the emergence of resistant mutants. The bacterium takes advantage of intrinsic and acquired resistance mechanisms to resist almost every antibiotic.
View Article and Find Full Text PDFArticle Synopsis
- Neonatal sepsis caused by multidrug-resistant K. pneumoniae is a growing concern, necessitating a better understanding of its antimicrobial susceptibility patterns and resistance mechanisms.
- The study analyzed K. pneumoniae strains from neonates over three years, focusing on β-lactam and fluoroquinolone resistance through molecular analysis.
- Results showed high resistance rates, with molecular docking revealing low antibiotic binding to target proteins, emphasizing the need for new treatment options due to the changing resistance profiles.