Effect of zinc oxide nanoparticles on the flexural strength of polymethylmethacrylate denture base resin.

Purpose: This study evaluated the flexural strength of polymethyl methacrylate (PMMA) reinforced with various concentrations of zinc oxide (Zn O) nanoparticles.

Materials And Methods: Nano ZnO was added in 0, 0.4, 0.

Granzyme B expression is enhanced in human monocytes by TLR8 agonists and contributes to antibody-dependent cellular cytotoxicity.

FcγRs are critical mediators of mAb cancer therapies, because they drive cytotoxic processes upon binding of effector cells to opsonized targets. Along with NK cells, monocytes are also known to destroy Ab-coated targets via Ab-dependent cellular cytotoxicity (ADCC). However, the precise mechanisms by which monocytes carry out this function have remained elusive.