Designing a Simple Quinoline-Based Chromo-Fluorogenic Receptor for Highly Specific Quantification of Copper (II) Ions: Environmental and Bioimaging Applications.

Many industries use copper metal ions (Cu ions), and their salts are utilized as supplemental materials in both agriculture and medicine. Identifying and monitoring these Cu ions in biological and environmental specimens is crucial due to their association with several health issues. In this investigation, we have designed a simple quinoline-based receptor (E)-3-(((2,4-di-tert-butyl-5-hydroxyphenyl)imino)methyl)-6-methoxyquinolin-2(1H)-one (QAP) containing imine functional groups to inspect its capability to identify metal ions in a semi-aqueous medium.

ZIF-67 derivatives of NiCoS Decorated in Salen-Complex Amine Functionalization GO Layers for High-Performance Applications in Supercapacitor Devices.

The study develops polyamine-functionalized graphene oxide-supported NiCoS nanomaterial using a metal-organic framework (MOF). This modification adds free amines and oxygen functionality to the graphene oxide electrode surface, resulting in the decrease in the 2 theta value from 11.2 to 7.

Dimercaprol-modified mesoporous silica nanoparticles for efficient removal of toxic mercury ions from aqueous solution.

A surface-modified mesoporous silica nanoparticle containing dimercaprol monomers was created utilizing the sol-gel condensation process, using tetraethyl orthosilicate (TEOS) as the silica source and poloxamer as the structure directing agent. To accomplish this synthesis, 3-glycidoxypropyl triethoxysilane (GPTS, 20 mol%) was incorporated into the silica walls during the sol-gel condensation process, along with TEOS. Furthermore, dimercaprol (DM) monomers were incorporated onto silica surfaces by a ring-opening reaction between GPTS epoxy groups, and dimercaprol hydroxyl groups.

Synthesis of bis(2-aminoethyl)amine functionalized mesoporous silica (SBA-15) adsorbent for selective adsorption of Pb ions from wastewater.

Rapid growth in the industry has released large quantities of contaminants, particularly metal discharges into the environment. Heavy metal poisoning in water bodies has become a major problem due to its toxicity to living organisms. In this study, we developed a 3-chloropropyl triethoxysilane incorporated mesoporous silica nanoparticle (SBA-15) based adsorbent utilizing the sol-gel process and Pluronic 123 (P123) as a structure-directing surfactant.

Conductive Polymer-Based Hydrogels for Wearable Electrochemical Biosensors.

Hydrogels are gaining popularity for use in wearable electronics owing to their inherent biomimetic characteristics, flexible physicochemical properties, and excellent biocompatibility. Among various hydrogels, conductive polymer-based hydrogels (CP HGs) have emerged as excellent candidates for future wearable sensor designs. These hydrogels can attain desired properties through various tuning strategies extending from molecular design to microstructural configuration.

Hyaluronic acid functionalized iron-platinum nanoparticles for photothermal therapy and photoacoustic imaging.

This study represents an innovative approach to construct multi-functional nanoplatforms for cancer diagnosis and therapy by combining hyaluronic acid (HA) with iron-platinum nanoparticles (FePt NPs). These HA-coated FePt NPs, referred to as FePt@HA NPs, demonstrated remarkable biocompatibility, high absorption, and excellent light-to-heat conversion properties in the near-infrared (NIR) region, making them ideal candidates for photothermal therapy (PTT). In vitro studies revealed their effective cancer cell eradication under NIR laser irradiation, while in vivo experiments on mice showcased their superior heating capabilities.

pNIPAm-Based pH and Thermoresponsive Copolymer Hydrogel for Hydrophobic and Hydrophilic Drug Delivery.

The regulated and targeted administration of hydrophobic and hydrophilic drugs is both promising and challenging in the field of drug delivery. Developing a hydrogel which is responsive to dual stimuli is considered a promising and exciting research area of study. In this work, melamine functionalized poly-N-isopropyl acrylamide-co-glycidyl methacrylate copolymer has been developed by copolymerizing glycidyl methacrylate (GMA) monomer with N-isopropyl acrylamide (NIPAm) and further functionalized with melamine units (pNIPAm-co-pGMA-Mela).

Synthesis of functionalized mesoporous silica nanoparticles for colorimetric and fluorescence sensing of selective metal (Fe) ions in aqueous solution.

The fabrication of red fluorescent hybrid mesoporous silica-based nanosensor materials has promised the bioimaging and selective detection of toxic pollutants in aqueous solutions. In this study, we present a hybrid mesoporous silica nanosensor in which the propidium iodide (PI) was used to conveniently integrate into the mesopore walls using bis(trimethoxysilylpropyl silane) precursors. Various characterization techniques including X-ray diffraction (XRD), Fourier-transform infrared (FTIR), N adsorption-desorption, zeta potential, particle size analysis, thermogravimetric, and UV-visible analysis were used to analyze the prepared materials.

Dual pH- and Thermo-Sensitive Poly(N-isopropylacrylamide-co-allylamine) Nanogels for Curcumin Delivery: Swelling-Deswelling Behavior and Phase Transition Mechanism.

Curcumin (Cur) is a beneficial ingredient with numerous bioactivities. However, due to its low solubility and poor bioavailability, its therapeutic application is limited. In this work, we prepared poly-N-isopropylacrylamide p(NIPAm) and polyallylamine p(Am)-based nanogel (p(NIPAm-co-Am)) NG for a dual pH- and temperature-sensitive copolymer system for drug delivery application.

L-lysine Functionalized Mesoporous Silica Hybrid Nanoparticles for pH-Responsive Delivery of Curcumin.

Stimuli-responsive controlled drug delivery systems have attracted the attention of researchers in recent decades due to their potential application in developing efficient drug carriers that are responsive to applied stimuli triggers. In this work, we present the synthesis of L-lysine (an amino acid that combines both amine and carboxylic acid groups in a single unit) modified mesoporous silica nanoparticles (MS@Lys NPs) for the delivery of the anticancer bioactive agent (curcumin, Cur) to cancer cells. To begin, mesoporous silica hybrid nanoparticles (MS@GPTS NPs) with 3-glycidoxypropyl trimethoxy silane (GPTS) were synthesized.

k-Carrageenan based magnetic@polyelectrolyte complex composite hydrogel for pH and temperature-responsive curcumin delivery.

The dual stimuli-responsive drug delivery system has attracted a lot of interest in controlled drug delivery to specific sites. The magnetic iron oxide nanoparticles integrated polyelectrolyte complex-based hydrogel (MPEC HG) system was developed in this work. First, magnetic nanoparticles were produced in situ in the synthetic polymer polyhexamethylene guanidine (PHMG).

L-Lysine-Modified pNIPAm-co-GMA Copolymer Hydrogel for pH- and Temperature-Responsive Drug Delivery and Fluorescence Imaging Applications.

The development of dual-stimuli-responsive hydrogels attracts much research interest owing to its unique stimuli-responsive characteristics. In this study, a poly-N-isopropyl acrylamide-co-glycidyl methacrylate-based copolymer was synthesized by incorporating N-isopropyl acrylamide (NIPAm) and a glycidyl methacrylate (GMA) monomer. The synthesized copolymer, pNIPAm-co-GMA was further modified with L-lysine (Lys) functional units and further conjugated with fluorescent isothiocyanate (FITC) to produce a fluorescent copolymer pNIPAAm-co-GMA-Lys hydrogel (HG).

Dramatic reduction of toxicity of Poly(hexamethylene guanidine) disinfectant by charge neutralization.

The current study aimed to investigate the toxicity of positively charged polyhexamethylene guanidine (PHMG) polymer and its complexation with different anionic natural polymers such as k-carrageenan (kCG), chondroitin sulfate (CS), sodium alginate (Alg.Na), polystyrene sulfonate sodium (PSS.Na) and hydrolyzed pectin (HP).

Thermosensitive Polymer-Modified Mesoporous Silica for pH and Temperature-Responsive Drug Delivery.

A mesoporous silica-based drug delivery system (MS@PNIPAm-PAAm NPs) was synthesized by conjugating the PNIPAm-PAAm copolymer onto the mesoporous silica (MS) surface as a gatekeeper that responds to temperature and pH changes. The drug delivery studies are carried out in vitro at different pH (7.4, 6.

Selective removal of copper (II) ions from aqueous solution using pyridyl-bridged mesoporous organosilica hybrid adsorbent.

The incorporation of active functional groups into the mesoporous organosilica hybrid materials is efficient for various applications. A newly designed mesoporous organosilica adsorbent was prepared using diaminopyridyl groups bridged-(bis-trimethoxy)organosilane (DAPy) precursor by using Pluronic P123 as structure directing template via sol-gel co-condensation method. The hydrolysis reaction of DAPy precursor and tetraethyl orthosilacate (TEOS) with a DAPy content of about 20 mol% to TEOS were incorporated into the mesopore walls of the mesoporous organosilica hybrid nanoparticles (DAPy@MSA NPs).

Update on Chitosan-Based Hydrogels: Preparation, Characterization, and Its Antimicrobial and Antibiofilm Applications.

Chitosan is a prominent biopolymer in research for of its physicochemical properties and uses. Each year, the number of publications based on chitosan and its derivatives increases. Because of its comprehensive biological properties, including antibacterial, antioxidant, and tissue regeneration activities, chitosan and its derivatives can be used to prevent and treat soft tissue diseases.

pH and Thermoresponsive PNIPAm-co-Polyacrylamide Hydrogel for Dual Stimuli-Responsive Controlled Drug Delivery.

The therapeutic delivery system with dual stimuli-responsiveness has attracted attention for drug delivery to target sites. In this study, we used free radical polymerization to develop a temperature and pH-responsive poly(N-isopropyl acrylamide)-co-poly(acrylamide) (PNIPAM-co-PAAm). PNIPAm-co-PAAm copolymer by reacting with N-isopropyl acrylamide (NIPAm) and acrylamide (Am) monomers.

Magnetic Application of Gadolinium Orthoferrite Nanoparticles Synthesized by Sol-Gel Auto-Combustion Method.

In this manuscript, we present the synthesis of gadolinium orthoferrite nanoparticles using the sol-gel auto-combustion technique. The obtained gadolinium orthoferrite nanoparticles were annealed at various temperatures, such as 800 °C, 900 °C, 1000 °C, and 1100 °C. The synthesized materials were analyzed by various instrumental characterizations.

Novel Approach in Biodegradation of Synthetic Thermoplastic Polymers: An Overview.

Biodegradation is necessary for water-soluble or water-immiscible polymers because they eventually enter streams which can neither be recycled nor incinerated. It is important to consider the microbial degradation of natural and synthetic polymers in order to understand what is necessary for biodegradation and the mechanisms involved. Low/high-density polyethylene is a vital cause of environmental pollution.

Thermo-Sensitive Poly (N-isopropylacrylamide-co-polyacrylamide) Hydrogel for pH-Responsive Therapeutic Delivery.

Stimuli-response polymeric nanoparticles have emerged as a carrier system for various types of therapeutic delivery. In this study, we prepared a dual pH- and thermo-sensitive copolymer hydrogel (HG) system (PNIPAm-co-PAAm HG), using N-isopropyl acrylamide (NIPAm) and acrylamide (AAm) as comonomers. The synthesized PNIPAm-co-PAAm HG was characterized using various instrumental characterizations.

Improved Harris Hawks Optimization with Hybrid Deep Learning Based Heating and Cooling Load Prediction on residential buildings.

In digital era, energy efficient building remains a hot research topic because of increasing concern regarding their environmental impact and energy consumption. Designing a suitable energy efficient building based on their layout namely overall areas, distribution of the glazing areas, orientation, height, and relative compactness. Such components directly impact the heating load (HL) and cooling load (CL) of residential buildings.

Improving the sensitivity for hydrogen peroxide determination with active VO nanocubes incorporated on mesoporous TiO.

The capacity to generate a constant signal response from an enzyme on an electrode surface has been a fascinating topic of research from the past three decades. To nourish the enzymatic activity during electrochemical reactions, the immobilization of dual enzymes on the electrode surface could prevent the enzymatic loss without denaturation and thus long-term stability can be achieved. For effective immobilization of dual enzymes, mesoporous materials are the ideal choice because of its numerous advantages such as 1.

Mesoporogen free synthesis of CuO/TiO heterojunction for ultra-trace detection of catechol in water samples.

Creating mesoporous architecture on the surface of metal oxides without using pore creating agent is significant interest in electrochemical sensors because these materials act as an efficient electron transfer process between the electrode interface and the analytes. Recent advances in mesoporous titanium dioxide (TiO)-based materials have acquired extraordinary opportunities because of their interconnected porous structure could act as a host for doping with various transition metals or heteroatoms to form a new type of heterojunction. Herein, a simple method is developed to synthesize mesoporous copper oxide (CuO) decorated on TiO nanostructures in which homogenous shaped CuO nanocrystals act as dopants decorated on the mesoporous structure of TiO, resulting in p-n heterojunction nanocomposite.

Volatile organic compounds in water matrices: Recent progress, challenges, and perspective.

Volatile organic compounds (VOCs) are a group of organic compounds that have a molecular structure containing carbon and their chemical properties allow them to be easily converted to steam and gas and remain for a long period of time and have diverse effects on the environment. The purpose of this study is determination of the concentration of VOCs such as alachlor, anthracene, benzene, bromoform, chloroform, heptachlor, isophorone, tetrachloroethylene, γ -chlordane, toluene, etc. in water matrices.

The influence of heterostructured TiO/ZnO nanomaterials for the removal of azo dye pollutant.

In recent times, there has been an inspired research on combining semiconducting metal oxides for improved industrial applications. Significantly, wastewater removal is concerned and the researchers are finding new methodologies for removing azo dyes that possess a high level of carcinogenic effects. In this connection, this work investigates the photocatalytic activity of synthesized TiO/ZnO nanocomposite irradiated under UV and visible light.