Elastomeric Ionic Hydrogel-Based Flexible Moisture-Electric Generator for Next-Generation Wearable Electronics.

Rapid consumption of traditional energy resources creates utmost research interest in developing self-sufficient electrical devices to progress next-generation electronics to a level up. To address the global energy crisis, moisture-electric generators (MEGs) are proving to be an emerging technology in this field, capable of powering wearable electronics by harvesting energy from abundantly available ambient moisture without any requirement for external/additional energy. Recent advances in MEGs generally utilize an inorganic, metal, or petroleum-based polymeric material as an active material, which may produce sufficient current but lacks the flexibility and stretchability required for wearable electronics.

Photo-annealable agarose microgels for jammed microgel printing: Transforming thermogelling hydrogel to a functional bioink.

Three-dimensional (3D) printing of hydrogel structures using jammed microgel inks offer distinct advantages of improved printing functionalities, as these inks are strain-yielding and self-recovering types. However, interparticle binding in granular hydrogel inks is a challenge to overcome the limited integrity and reduced macroscale modulus prevalent in the 3D printed microgel scaffolds. In this study, we prepared chemically annealable agarose microgels through a process of xerogel rehydration, applying a low-cost and high throughput method of spray drying.

Synthesis of gallic acid-grafted epoxidized natural rubber and its role in self-healable flexible temperature sensors.

Developing a flexible temperature sensor with appreciable sensitivity is critical for advancing research related to flexible electronics. Although various flexible sensors are available commercially, most such temperature sensors are made from polymeric materials obtained from petrochemical resources. Such sensors will contribute to electronic waste and increase the carbon footprint after usage.

Unusually high clarithromycin resistance in subsp. isolated from human gastric epithelium.

subsp. is a rapidly growing facultative intracellular pathogen that usually infects human lung and skin epithelium. Recently, we and another group have shown that it also has the potential to colonize human gastric epithelium, but its significance with respect to gastric diseases remains unclear.

Biosensors for point-of-care testing and personalized monitoring of gastrointestinal microbiota.

The gastrointestinal (GI) microbiota is essential in maintaining human health. Alteration of the GI microbiota or gut microbiota (GM) from homeostasis (i.e.

Correction: Engineered nanostructures within sol-gel bioactive glass for enhanced bioactivity and modulated drug delivery.

Correction for 'Engineered nanostructures within sol-gel bioactive glass for enhanced bioactivity and modulated drug delivery' by Lakshmi M. Mukundan , , 2022, https://doi.org/10.

Engineered nanostructures within sol-gel bioactive glass for enhanced bioactivity and modulated drug delivery.

The engineering of nanocrystalline phase in amorphous oxide materials such as bioactive glass is emerging as a new area of great technological and scientific interest in the field of biomaterials. This study reports for the first time the infusion of apatite nanocrystals in sol-gel-derived bioactive glass using P123 as the structure-directing agent. The synthesis of a multicomponent 80SiO-15CaO-5PO bioactive glass material having a hierarchically ordered mesoporous structure with uniformly grown nanocrystals of apatite was achieved through a sono-assisted surfactant-templated sol-gel method.

Gastrointestinal microbiome in the context of Helicobacter pylori infection in stomach and gastroduodenal diseases.

Infectious origins of a set of severe gastroduodenal diseases viz. gastritis, duodenal ulcer, gastric ulcer, gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue (MALT) lymphoma were appreciated only after the discovery of H. pylori in 1983.

Metal Ion Augmented Mussel Inspired Polydopamine Immobilized 3D Printed Osteoconductive Scaffolds for Accelerated Bone Tissue Regeneration.

Critical bone defects with a sluggish rate of auto-osteoconduction and imperfect reconstruction are motivators for the development of an alternate innovative approach for the regeneration of bone. Tissue engineering for bone regeneration signifies an advanced way to overcome this problem by creating an additional bone tissue substitute. Among different fabrication techniques, the 3D printing technique is obviously the most efficient and advanced way to fabricate an osteoconductive scaffold with a controlled porous structure.

Peptic Ulcer and Gastric Cancer: Is It All in the Complex Host-Microbiome Interplay That Is Encoded in the Genomes of "Us" and "Them"?

It is increasingly being recognized that severe gastroduodenal diseases such as peptic ulcer and gastric cancer are not just the outcomes of infection in the stomach. Rather, both diseases develop and progress due to the perfect storms created by a combination of multiple factors such as the expression of different virulence proteins, consequent human immune responses, and dysbiosis in gastrointestinal microbiomes. In this mini review, we have discussed how the genomes of and other gastrointestinal microbes as well as the genomes of different human populations encode complex and variable virulome-immunome interplay, which influences gastroduodenal health.

Elastomeric microwell-based triboelectric nanogenerators by in situ simultaneous transfer-printing.

Self-powered tactile module-based electronic skins incorporating triboelectric nanogenerator (TENG) appears to be a worthwhile alternative for smart monitoring devices in terms of sustainable energy harvesting. On top of it, ultra-stretchability and detection sensitivity are imperative to mimic human skin. We report, for the first time, a metal-free single electrode TENG-based self-powered tactile module comprising of microwells (diameters 2 μm and 200 nm, respectively) on fluoroelastomer (FKM) and laser induced graphene (LIG) electrodes by in situ simultaneous transfer printing method.

Influence of Nanofillers on Adhesion Properties of Polymeric Composites.

Nanofillers (NFs) are becoming a ubiquitous choice for applications in different technological innovations in various fields, from biomedical devices to automotive product portfolios. Potential physical attributes like large surface areas, high surface energy, and lower structural imperfections make NFs a popular filler over microfillers. One specific application, where NFs are finding applications, is in adhesive science and technology.

Antimicrobial resistance and virulence in Helicobacter pylori: Genomic insights.

Microbes evolve rapidly by modifying their genome through mutations or acquisition of genetic elements. Antimicrobial resistance in Helicobacter pylori is increasingly prevalent in India. However, limited information is available about the genome of resistant H.

in Human Stomach: The Inconsistencies in Clinical Outcomes and the Probable Causes.

Pathogenic potentials of the gastric pathogen, , have been proposed, evaluated, and confirmed by many laboratories for nearly 4 decades since its serendipitous discovery in 1983 by Barry James Marshall and John Robin Warren. is the first bacterium to be categorized as a definite carcinogen by the International Agency for Research on Cancer (IARC) of the World Health Organization (WHO). Half of the world's population carries , which may be responsible for severe gastric diseases like peptic ulcer and gastric cancer.

Low Abundance in the Lower Gut Microbiota Is Associated With -Related Gastric Ulcer and Gastric Cancer.

infection in stomach leads to gastric cancer, gastric ulcer, and duodenal ulcer. More than 1 million people die each year due to these diseases, but why most -infected individuals remain asymptomatic while a certain proportion develops such severe gastric diseases remained an enigma. Several studies indicated that gastric and intestinal microbiota may play a critical role in the development of the -associated diseases.

Sono-Assembly of the [Arg-Phe] Octapeptide into Biofunctional Nanoparticles.

High-frequency ultrasound treatment is found to be a one-pot green technique to produce peptide-based nanostructures by ultrasound assisted self-assembly of oligopeptides. [Arg-Phe] octapeptides, consisting of alternating arginine (Arg/R) and phenylalanine (Phe/F) sequences, were subjected to 430 kHz ultrasound in aqueous solution in the absence of any external agents, to form [RF] nanoparticles ([RF]-NPs), ~220 nm in diameter. A comprehensive analysis of the obtained nanoparticles demonstrated that the aromatic moieties of the oligopeptides can undergo oxidative coupling to form multiple oligomeric species, which then self-assemble into well-defined fluorescent nanoparticles.

Mycobacterium abscessus infection in the stomach of patients with various gastric symptoms.

Development of gastric diseases such as gastritis, peptic ulcer and gastric cancer is often associated with several biotic and abiotic factors. Helicobacter pylori infection is such a well-known biotic factor. However, not all H.

Promoted Osteoconduction of Polyurethane-Urea Based 3D Nanohybrid Scaffold through Nanohydroxyapatite Adorned Hierarchical Titanium Phosphate.

The lack of optimal physiological properties, bacterial colonization, and auto-osteoinduction, are the foremost issues of orthopedic implantations. In terms of bone healing, many researchers have reported the release of additional growth factors of the implanted biomaterials to accelerate the bone regeneration process. However, the additional growth factor may cause side effects such as contagion, nerve pain, and the formation of ectopic bone.

Biocompatible polyvinyl alcohol and RISUG blend polymeric films with spermicidal potential.

Majority of the commercially available vaginal contraceptives encompasses cervicovaginal membrane disrupting detergent molecules as pharmacologically active ingredients. Development of a tissue-compatible vaginal contraceptive agent is necessary to circumvent the existing demand for female contraception in the reproductive healthcare sector. With this objective, the present study delineates the use of RISUG based non-hormonal female contraceptive films.

Impact of styrene maleic anhydride (SMA) based hydrogel on rat fallopian tube as contraceptive implant with selective antimicrobial property.

Development of non-hormonal female contraception is a need to combat against increasing population growth. The presently available short term or long term female contraceptives and sterilization methods have their own restrictions and side effects. With this objective, herein, we describe an innovative insight about the use of hydrogel formulation consisting of Styrene Maleic Anhydride (SMA) dissolved in Dimethyl Sulfoxide (DMSO) as non-hormonal fallopian tube contraceptive implant.

Core-Shell Nanofibrous Scaffold Based on Polycaprolactone-Silk Fibroin Emulsion Electrospinning for Tissue Engineering Applications.

The vast domain of regenerative medicine comprises complex interactions between specific cells' extracellular matrix (ECM) towards intracellular matrix formation, its secretion, and modulation of tissue as a whole. In this domain, engineering scaffold utilizing biomaterials along with cells towards formation of living tissues is of immense importance especially for bridging the existing gap of late; nanostructures are offering promising capability of mechano-biological response needed for tissue regeneration. Materials are selected for scaffold fabrication by considering both the mechanical integrity and bioactivity cues they offer.

Effect of Plasma, Gamma and Chemically Surface Modified MWNTs on the Rheological and Electrical Properties of Ethylene Methyl Acrylate (EMA) Nanocomposites.

Surface modifications of the MWNTs have been carried out by treating the as received MWNTs with plasma (N2 and O2), piranha (H2SO4/H2O2) and γ-ray irradiation under well specified conditions. Surface modifications introduce polar functional groups onto MWNTs surfaces. A variety of characterization techniques including FTIR, Raman spectroscopy, and XPS were employed to characterize the functional group introduced onto MWNTs after the modification.