Characterizing the Effects of Adding Virtual and Augmented Reality in Robot-Assisted Training.

Extended reality (XR) technology combines physical reality with computer synthetic virtuality to deliver immersive experience to users. Virtual reality (VR) and augmented reality (AR) are two subdomains within XR with different immersion levels. Both of these have the potential to be combined with robot-assisted training protocols to maximize postural control improvement.

Reoperative aortic root surgery: single-center long-term outcomes and literature review.

Background And Objective: Reoperative aortic root surgery has become more and more common over the years and is considered high-risk, with significantly worse outcomes compared to first-procedure root surgery. At our institution, this kind of surgery is frequently performed. The aim of the present review is to describe currently available literature on reoperative surgery on the aortic root in terms of patients' population, indications for surgery and outcomes and to present our center's experience on the matter.

Robotic Postural Training With Epidural Stimulation for the Recovery of Upright Postural Control in Individuals With Motor Complete Spinal Cord Injury: A Pilot Study.

Activity-based training and lumbosacral spinal cord epidural stimulation (scES) have the potential to restore standing and walking with self-balance assistance after motor complete spinal cord injury (SCI). However, improvements in upright postural control have not previously been addressed in this population. Here, we implemented a novel robotic postural training with scES, performed with free hands, to restore upright postural control in individuals with chronic, cervical ( = 5) or high-thoracic ( = 1) motor complete SCI, who had previously undergone stand training with scES using a walker or a standing frame for self-balance assistance.

Training Postural Balance Control with Pelvic Force Field at the Boundary of Stability.

This study characterizes the effects of a postural training program on balance and muscle control strategies in a virtual reality (VR) environment. The Robotic Upright Stand Trainer (RobUST), which applies perturbative forces on the trunk and assistive forces on the pelvis, was used to deliver perturbation-based balance training (PBT) in a sample of 10 healthy participants. The VR task consisted of catching, aiming, and throwing a ball at a target.

Frozen elephant trunk in acute aortic dissection: a literature review.

Background: Acute aortic dissection is a life-threatening condition that requires urgent surgical treatment. The frozen elephant trunk (FET) technique, including the Thoraflex hybrid prosthesis, has emerged as an effective strategy for treating complex aortic pathologies. With the widespread application of the FET technique, it continues to evolve, aiming to simplify procedures and reduce complications.

Infant Sitting and Multi-Directional Reaching Skill.

We tested twenty-one 6- to 10-month-old infants with a wide range of sitting experience in forward and rightward reaching during unsupported sitting on the floor. Sessions were video-recorded for further behavioral and machine learning-based kinematic analyses. All infants, including novice sitters, successfully touched and grasped toys in both directions.

EpiGe: A machine-learning strategy for rapid classification of medulloblastoma using PCR-based methyl-genotyping.

Molecular classification of medulloblastoma is critical for the treatment of this brain tumor. Array-based DNA methylation profiling has emerged as a powerful approach for brain tumor classification. However, this technology is currently not widely available.

Study protocol for a randomised controlled trial to determine the efficacy of an intensive seated postural intervention delivered with robotic and rigid trunk support systems.

Introduction: Children with cerebral palsy (CP) classified as gross motor function classification system (GMFCS) levels III-IV demonstrate impaired sitting and reaching control abilities that hamper their overall functional performance. Yet, efficacious interventions for improving sitting-related activities are scarce. We recently designed a motor learning-based intervention delivered with a robotic Trunk-Support-Trainer (TruST-intervention), in which we apply force field technology to individualise sitting balance support.

Assessing engagement in rehabilitation: development, validity, reliability, and responsiveness to change of the Rehabilitation Observation Measure of Engagement (ROME).

Purpose: We describe the development of an observational video coding tool, the Rehabilitation Observation Measure of Engagement (ROME), to quantify engagement in rehabilitative settings at the person (internal state of an individual) and between-system (interaction between individuals) level.

Methods: Forty-nine children with unilateral spastic cerebral palsy (29 males; Age:  = 9.28 yrs, SD = 3.

Effects of Boundary-Based Assist-as-Needed Force Field on Lower Limb Muscle Synergies During Standing Posture Training.

The boundary-based assist-as-needed (BAAN) force field is widely used in robotic rehabilitation and has shown promising results in improving trunk control and postural stability. However, the fundamental understanding of how the BAAN force field affects the neuromuscular control remains unclear. In this study, we investigate how the BAAN force field impacts muscle synergy in the lower limbs during standing posture training.

3D printing as surgical planning and training in pediatric endoscopic skull base surgery - Systematic review and practical example.

Background: Pediatric endoscopic skull base surgery is challenging due to the intricate anatomy of the skull base and the presence of tumors with varied pathologies. The use of three-dimensional (3D) printing technologies in skull base surgeries has been found to be highly beneficial. A systematic review of the literature was performed to investigate the published studies that reported the effectiveness of 3D printing in pediatric endoscopic skull base surgery.

Dynamic sitting in infants: Limits of stability.

Background: Limits of stability-defined by the maximum distances a person is willing to reach without falling or changing the base of support-are measures of dynamic balance.

Research Question: What are infants' sitting stability limits in the forward and right directions?

Methods: Twenty-one 6- to 10-month old infants participated in this cross-sectional study. To incentivize infants to reach beyond arm's length, caregivers began by holding a toy close to their infants at shoulder height.

A motor learning-based postural intervention with a robotic trunk support trainer to improve functional sitting in spinal cord injury: case report.

Study Design: Single-subject-research-design.

Objectives: To improve seated postural control in a participant with spinal cord injury (SCI) with a robotic Trunk-Support-Trainer (TruST).

Setting: Laboratory.

A Deep-Learning Based Real-Time Prediction of Seated Postural Limits and Its Application in Trunk Rehabilitation.

Seated postural limit defines the boundary of a region such that for any excursions made outside this boundary a subject cannot return the trunk to the neutral position without additional external support. The seated postural limits can be used as a reference to provide assistive support to the torso by the Trunk Support Trainer (TruST). However, fixed boundary representations of seated postural limits are inadequate to capture dynamically changing seated postural limits during training.

Redistributing Ground Reaction Forces During Squatting Using a Cable-Driven Robotic Device.

Squatting is a dynamic task that is often done for strengthening and improving balance. Most squat training systems partially support body weight. However, one of the benefits of a squat exercise is efficiently distributing the body weight among the feet while maintaining stability.

Langerhans cell histiocytosis. Advances in pathogenesis and clinical practice.

Langerhans cell histiocytosis (LCH) is a type of myeloid neoplasia that can affect different organs or tissues and exhibits substantial variability in its clinical presentation and biological behaviour, so it may mimic different diseases. Performance of different clinical assessments and laboratory and imaging tests is recommended to determine the extent of involvement, which may be of a single location or multisystemic, and the presence or absence of dysfunction in risk organs, such as the haematopoietic system, liver and spleen. The diagnosis must be confirmed by histological examination of a biopsy sample.

Robotic upright stand trainer (RobUST) and postural control in individuals with spinal cord injury.

Context/objective: Assessed feasibility and potential effectiveness of using a novel robotic upright stand trainer (RobUST) to deliver postural perturbations or provide assistance-as-needed at the trunk while individuals with spinal cord injury (SCI) performed stable standing and self-initiated trunk movements. These tasks were assessed with research participants' hands on handlebars for self-balance assistance (hands on) and with hands off (free hands).

Design: Proof of concept study.

Therapeutic alternatives in chronic thromboembolic pulmonary hypertension: from pulmonary endarterectomy to balloon pulmonary angioplasty to medical therapy. State of the art from a multidisciplinary team.

Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare disease with a very complex pathophysiology differing from other causes of pulmonary hypertension (PH). It is an infrequent consequence of acute pulmonary embolism that is frequently misdiagnosed. Pathogenesis has been related to coagulation abnormalities, infection or inflammation, although these disturbances can be absent in many cases.