Rate of peripheral glucose change during cognitive testing predicts performance in diabetes mellitus.

Background: The reason for cognitive deterioration in diabetes mellitus (DM) remains unknown. One suggestion is that despite elevated glucose levels, patients with DM generally have difficulty utilizing glucose during cognitive tasks. This assumption was tested in the present study.

Improving glycemic control: the role of leisure activities and intrinsic motivation in older type 2 diabetic men.

Greater frequency of involvement with sedentary leisure activities may be associated with better disease outcomes. In this study, the frequency of engagement in sedentary leisure activities served as a construct employed to reflect the possible association between motivation and adherence with diabetic regimen. Up to a point, the higher frequency of leisure behaviors correlated with improved glycemic control and triglyceride levels in older type 2 diabetic male veterans (N = 49).

Blood glucose levels before and after cognitive testing in diabetes mellitus.

The primary indices of diabetes mellitus (DM), including hemoglobin A1c (HbA1c) and fasting glucose, appear to be only moderately predictive of the cognitive impairments exhibited by patients with DM. There is evidence that in DM the ability to utilize glucose is compromised and the authors hypothesized that this difficulty might be relevant to the study of cognitive function in DM. Thus, the authors examined the relationship between cognitive performance and changes in peripheral glucose from the start to the conclusion of cognitive testing.

Parents matter: intergenerational influences of diabetes mellitus on glycemic control and morbidity in older type 2 diabetic males.

In a cross-sectional study, the effects of disease duration of type 2 diabetes mellitus (DM) were examined along with parent history of DM on disease-related outcome variables. Specifically, the moderating role of parent history of DM on outcome variables was examined. Participants were 53 male veterans with DM.

Light to moderate alcohol drinking is associated with higher cognitive function in males with type 2 diabetes.

This study examined cognitive function in males with type 2 diabetes who drank light to moderate levels of alcohol in comparison to abstainers. Patients who abstained from alcohol use (Abstainer; N = 99) were compared to patients who were current drinkers (Drinker; N = 20) with respect to demographic, clinical, and cognitive variables. There were no significant differences between the Drinker and Abstainer groups in demographic and general clinical variables (p values > .

Race moderates age-related cognitive decline in type 2 diabetes.

The age-related rate of cognitive decline in patients with diabetes mellitus has received relatively little attention. In this cross-sectional study, Caucasian (N = 145) and African American (N = 25) males with diabetes mellitus were recruited to examine age-related changes in cognitive performance. It is known that African Americans with diabetes mellitus are at increased risk for more frequent and more severe diabetes-related complications.

The endocannabinoid system: a promising novel mechanistic pathway in the cardiometabolic syndrome.

The endocannabinoid system (ECS) is a neuroendocrine system that modulates several cardiometabolic processes. An overactive ECS is implicated as a significant contributor to the cardiometabolic syndrome and obesity, in addition to a large number of other physiologic processes. Endocannabinoid receptors have been detected centrally and peripherally, regulating appetite, food intake, metabolism, and storage.