Addison's Disease Caused by Tuberculosis: Diagnostic and Therapeutic Difficulties.

Objectives: To demonstrate difficulties in diagnosing and treating Addison's disease caused by tuberculosis.

Materials And Methods: We present a clinical case and review of the literature.

Results: A 62-year-old man presented with gastrointestinal symptoms, weight loss and enlarged adrenal glands.

Nasal nitric oxide levels and nasal polyposis in children and adolescents with cystic fibrosis.

Importance: The counterintuitive decrease of exhaled nitric oxide (NO) levels in a severe inflammatory disorder like cystic fibrosis (CF) is only scarcely understood. Because NO is important in a variety of regulatory processes in the lung, including host defense, inflammation, and bronchomotor control, it is necessary to search for clarifying mechanisms.

Objectives: To explore whether fractional exhaled NO (FENO) and nasal NO (nNO) levels are associated with CF genotype, nutritional status, presence of nasal polyps, pulmonary function, and airway colonization with Staphylococcus aureus and Pseudomonas aeruginosa in children with CF, and to investigate the effect of functional endoscopic sinus surgery (FESS) on FENO and nNO levels in children with CF and persistent sinonasal disease.

Controlled trial of cycled antibiotic prophylaxis to prevent initial Pseudomonas aeruginosa infection in children with cystic fibrosis.

Background: Initial pulmonary Pseudomonas aeruginosa infection in patients with cystic fibrosis (CF) is currently treated with intensive antibiotic therapy. At this stage, inflammation and tissue injury might have already occurred. Moreover, bacterial eradication is not always achieved.