Publications by authors named "Sanne G J Mourmans"
Article Synopsis
- The study investigates the prevalence and impact of inter-atrial block (IAB) as an indicator of electrical dysfunction in patients with heart failure with preserved ejection fraction (HFpEF).
- It examines two groups: ambulatory HFpEF patients and those recently hospitalized, assessing their risk for adverse events like hospitalization and death.
- Findings suggest that different stages of electrical atrial dysfunction significantly predict adverse outcomes, indicating that patients without dysfunction might require less intensive management.
Aims: Nocturnal hypoxaemic burden, quantified as time spent with oxygen saturation below 90% (T90), is an established independent predictor of mortality in heart failure (HF) with reduced ejection fraction. The prognostic value of T90 in HF with preserved ejection fraction (HFpEF) is unknown. This study aims to determine the association of T90 with adverse outcomes in HFpEF.
View Article and Find Full Text PDFCoronary vasomotor dysfunction, an important underlying cause of angina and nonobstructive coronary arteries (ANOCA), encompassing coronary vasospasm, coronary endothelial dysfunction, and/or coronary microvascular dysfunction, is clinically assessed by invasive coronary function testing (ICFT). As ICFT imposes a high burden on patients and carries risks, developing noninvasive alternatives is important. We evaluated whether coronary vasomotor dysfunction is a component of systemic microvascular endothelial and smooth muscle dysfunction and can be detected using laser speckle contrast analysis (LASCA).
View Article and Find Full Text PDFSystemic microvascular regression and dysfunction are considered important underlying mechanisms in heart failure with preserved ejection fraction (HFpEF), but retinal changes are unknown. This prospective study aimed to investigate whether retinal microvascular and structural parameters assessed using optical coherence tomography angiography (OCT-A) differ between patients with HFpEF and control individuals (i.e.
View Article and Find Full Text PDFHeart failure with preserved ejection fraction (HFpEF) is a condition with increasing incidence, leading to a health care problem of epidemic proportions for which no curative treatments exist. Consequently, an urge exists to better understand the pathophysiology of HFpEF. Accumulating evidence suggests a key pathophysiological role for coronary microvascular dysfunction (MVD), with an underlying mechanism of low-grade pro-inflammatory state caused by systemic comorbidities.
View Article and Find Full Text PDFArticle Synopsis
- Heart failure is when the heart can't pump blood well, often caused by heart diseases or problems with the heart muscle, called cardiomyopathies.
- The Maastricht Cardiomyopathy registry aims to help doctors diagnose and treat these heart problems better and earlier.
- They are collecting a lot of patient information over 15 years to find patterns and improve treatment, and other medical centers can easily join the research too.