Publications by authors named "Sanna Hellsten"
A new chemical recycling method for waste cotton is presented that allows the production of virgin textile fibers of substantially higher quality than that from the mechanical recycling methods that are used currently. Cotton postconsumer textile wastes were solubilized fully in the cellulose-dissolving ionic liquid 1,5-diazabicyclo[4.3.
View Article and Find Full Text PDFA process concept where a solvent removal unit is integrated to a steady-state recycling chromatography process (SSR-SR) offers a possibility to significantly increase the performance of single column chromatographic separation. The advantages of solvent removal for a difficult separation task at conditions typical for industrial scale chromatography were demonstrated by investigating the performance of SSR-SR in separation of glucose and galactose. Two limits for the extent of solvent removal were imposed: maximum total concentration of the solution fed into the column (viscosity limit) and the maximum total concentration achievable in the solvent removal unit (solubility or osmotic pressure limit).
View Article and Find Full Text PDFArticle Synopsis
- The study examined the stability of high indomethacin (IMC) content formulations using ordered mesoporous silica materials MCM-41 and SBA-15 after three months of storage in stressed conditions (30°C/56% RH).
- Overall, while the physical stability was deemed satisfactory, MCM-41 samples exhibited notable chemical stability issues, indicated by reduced drug loading and unexpected peaks in HPLC chromatograms.
- Drug release was initially rapid at pH 1.2 for the mesoporous formulations, maintaining similar profiles post-stress, with even quicker release observed at a higher pH of 6.8, highlighting the need for further investigation into chemical stability factors in these formulations for effective oral drug delivery.