Publications by authors named "Sanli H"
Mycosis fungoides (MF) is the most prevalent type of cutaneous T cell lymphomas. Studies on the prognosis of MF are limited, and no research exists on the potential of artificial intelligence to predict MF prognosis. This study aimed to compare the predictive capabilities of various machine learning (ML) algorithms in predicting progression, treatment response, and relapse and to assess their predictive power against that of the Cox proportional hazards (CPH) model in patients with early-stage MF.
View Article and Find Full Text PDFBackground: Mycosis fungoides (MF) is the most common cutaneous lymphoma with a chronic disease course. MF patients may also suffer from systemic comorbidities such as cardiovascular and metabolic diseases.
Methods: In this study, we aimed to evaluate the demographic and clinical features of MF patients registered in the MF-TR registry system and to examine the relationship of these features with systemic comorbidities.
Background: As the majority of T-cell lymphomas lack CD20 expression, cases of mycosis fungoides (MF) exhibiting aberrant CD20 expression are exceedingly uncommon.
Objectives: To comprehensively evaluate the clinical, histopathological and prognostic features of seven patients diagnosed with CD20+ MF.
Methods: This retrospective study involved seven cases of MF with aberrant CD20 expression.
Background/purpose: Interferon (IFN)-a is often used in combination with psoralen plus ultraviolet A (PUVA) in patients with mycosis fungoides (MF) refractory to skin-targeted therapies in early or advanced stages. The main objective is to evaluate the effectiveness of combined PUVA and low-dose IFN-α-2a therapy in patients with early- and advanced-stage MF.
Methods: Sixty-eight patients who received a combination of PUVA twice or thrice a week and INF-a 3 MU thrice a week for at least 3 months were reviewed retrospectively.
Article Synopsis
- The study aimed to explore skin changes in patients with acromegaly, a condition often revealed through dermatological symptoms, and examine how these changes relate to disease remission and other hormonal disorders.
- Involving 278 acromegaly patients across 14 healthcare centers, dermatological evaluations revealed common skin conditions like skin tags (52.5%), cherry angiomas (47.4%), and varicose veins (33%).
- Significant associations were found between certain skin conditions and hormonal issues, such as higher rates of diabetes and hypothyroidism in patients with varicose veins, while hypertrichosis was more common in patients who had not achieved remission.
Risk of skin cancers in mycosis fungoides patients receiving PUVA therapy: A real-life experience from a single tertiary center.
Photodermatol Photoimmunol Photomed
September 2023
Background: Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. Skin-directed therapies, including phototherapy, are the first-line treatment modalities. Psoralen plus ultraviolet A light photochemotherapy (PUVA) is quite effective in controlling the disease; however, long-term adverse effects, particularly carcinogenesis, are the cons of this treatment.
View Article and Find Full Text PDFAllogeneic hematopoietic stem cell transplantation (AHSCT) is a promising strategy for treatment of heavily pretreated mycosis fungoides/Sezary syndrome (MF/SS). Herein, we aimed to evaluate the outcomes of AHSCT for heavily pretreated patients with MF/SS retrospectively. This analysis included consecutive 19 patients with MF/SS who received 20 AHSCT between 2012-2021 in our transplant center.
View Article and Find Full Text PDFHypothesis: It is possible to detect when misplacement and malposition of the cochlear implant (CI) electrode array has occurred intraoperatively through different investigations. We aim to explore the literature surrounding cochlear implant misplacements and share our personal experience with such cases to formulate a quick-reference guide that may be able to help cochlear implant teams detect misplacements early.
Background: Misplacement and malposition of a cochlear implant array can lead to poor hearing outcomes.
Introduction: The COVID-19 pandemic drastically changed the priorities in healthcare services; outpatient management of acne has changed during this period.
Objectives: We aimed to investigate treatment practices, outcomes and identify modified follow-up schedules applied during the pandemic.
Methods: The patients who were admitted to dermatology outpatient clinic between March 13 and July 13, 2020, were included.
Article Synopsis
- - The study aimed to determine the incidence, demographics, and clinical characteristics of pemphigoid diseases in Turkey, as existing data were limited.
- - Researchers analyzed 295 patients diagnosed with pemphigoid over one year, finding a higher prevalence of bullous pemphigoid, which accounted for 93.2% of cases, with an overall incidence rate of 3.55 cases per million years.
- - The study highlighted that gliptin derivative drugs might be a common trigger for bullous pemphigoid, and cardiovascular (27.8%) and neurological (23.7%) diseases were frequently observed alongside these conditions.
Background: Vaccines that incorporate multiple SARS-CoV-2 antigens can further broaden the breadth of virus-specific cellular and humoral immunity. This study describes the development and immunogenicity of SARS-CoV-2 VLP vaccine that incorporates the four structural proteins of SARS-CoV-2.
Methods: VLPs were generated in transiently transfected HEK293 cells, purified by multimodal chromatography, and characterized by tunable-resistive pulse sensing, AFM, SEM, and TEM.
Objective: The purpose of this study was to characterize a cohort of patients with nonauditory side-effects (NASx) following cochlear implant (CI) surgery.
Study Design: Retrospective case review.
Setting: Tertiary referral center.
A rare case of granulomatous slack skin associated with rheumatoid arthritis.
Indian J Dermatol Venereol Leprol
January 2022
Objective: To present our data evaluating the feasibility of simultaneous cochlear implantation with resection of acoustic neuroma.
Methods: This paper describes a case series of eight adult patients with a radiologically suspected acoustic neuroma, treated at a tertiary referral centre in Newcastle, Australia, between 2012 and 2015. Patients underwent cochlear implantation concurrently with removal of an acoustic neuroma.
Objectives: To assess the effect on impedance levels of intraoperative reinsertion of a cochlear implant (CI) array compared with matched controls.
Study Design: Retrospective patient review.
Setting: Cochlear implant center.
Folliculotropic mycosis fungoides (FMF) is characterized by a broad clinical spectrum and worse prognosis compared to classical MF. This study aimed to evaluate the clinical characteristics, treatment modalities and long-term outcome and risk factors for progression and survival of FMF patients. We conducted a single-center retrospective study and reviewed 53 patients diagnosed with FMF between 1990 to 2019 in a referral center at Ankara University, Turkey.
View Article and Find Full Text PDFObjective: To compare the speech perception outcomes for patients with preoperative severe versus profound hearing loss with a cochlear implant (CI).
Study Design: Retrospective patient review.
Setting: Cochlear implant program.
Background And Objective: Less than 5% of cases of mycosis fungoides (MF) present with a cytotoxic/suppressor CD8 phenotype. This study aimed to evaluate the clinical characteristics, treatment modalities, and clinical course in CD8 MF patients.
Methods: In a retrospective analysis of 353 MF patients in a referral center at Ankara University, Turkey, 29 patients that were diagnosed with CD8 MF were included in the study.
Objective: Examine postoperative speech perception outcomes in a large vestibular aqueduct syndrome (LVAS) patients at a major cochlear implantation center.
Study Design: Retrospective analysis of the Sydney Cochlear Implant Centre (SCIC) database and medical records from January 1994 to December 2015 was performed.
Setting: Tertiary referral center.