Publications by authors named "Sankarshana R Nagaraja"
Article Synopsis
- Various cellular quality control mechanisms, like ribosome-associated chaperones, help maintain proteostasis by preventing misfolding of proteins during translation.
- This study hypothesizes that importins, which usually assist in transporting proteins into the nucleus, might also bind to newly formed protein chains during translation, rather than just after.
- By analyzing all importins in yeast, the researchers found some that associate with potentially unstable proteins, indicating that importins and other chaperones work together to ensure proper protein folding and prevent aggregation.
