Publications by authors named "Sankari Malaippan"

It is of interest to formulate and evaluate herbal trio gel containing brown flax seed extract, carbopol, and carboxymethyl cellulose and to assess the antimicrobial, anti-inflammatory activity along with quality analysis using SEM and FTIR. The brown flax seeds were grinded into a fine powder and supercritical fluid was prepared which was mixed with CMC and carbopol. The formulation was checked for antimicrobial, anti-inflammatory activity, surface characteristics with SEM and FTIR.

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Background: Periodontitis is a destructive inflammatory disorder of the periodontium caused by the destruction of periodontal tissues namely the PDL, cementum, alveolar bone, and gingiva. Once these tissues are lost, the foremost goal of periodontal therapy is to regenerate the diseased tissues if possible to their original form, architecture, and function. Various regenerative procedures were employed and still a gap was found in achieving the goal.

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Aim: The aim of this study was to determine the association between IL-1B (+3954) gene polymorphism and chronic periodontitis in a sample of the south Indian population.

Settings And Design: This study employed a cross-sectional design involving individuals from the state of Tamil Nadu in the southern part of India.

Materials And Methods: Genomic DNA was obtained from the white blood cells of 30 patients with chronic periodontitis (18 males and 12 females) and 31 healthy controls (20 males and 11 females).

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