Ethyl acetate extract from marine sponge Hyattella cribriformis exhibit potent anticancer activity by promoting tubulin polymerization as evidenced mitotic arrest and induction of apoptosis.

Background: Marine sponges are important sources of bioactive compounds.

Objective: This study investigated the anticancer properties of Hyattella cribriformis ethyl acetate (EA) fraction in various cancer and normal cell lines.

Materials And Methods: anticancer assay was carried out in 15 cell lines to evaluate the anticancer potential of the EA fraction.