Prognostic Significance of Epidermal Growth Factor Receptor in Patients of Glioblastoma Multiforme.

Introduction: Glioblastoma Multiforme (GBM) is the most aggressive glial tumour with hallmark characteristics of rampant proliferation of glial cells along with high pleomorphism, necrosis, endothelial proliferation and high MIB-1 labeling index (cell proliferation marker). These tumours are managed by surgery followed by Radiotherapy (RT), Chemotherapy (CT) and adjuvant CT Temozolomide (TMZ).

Aim: To evaluate Epidermal Growth Factor Receptor (EGFR) protein expression in GBM patients.