A sequential Friedländer and anionic benzannulation strategy for the regiodefined assembly of unsymmetrical acridines.

An efficient sequential double-annulation strategy has been developed to afford a series of unsymmetrical acridines with high yield and regioselectivity for the first time. This simple protocol enables the sequential assembly of two aromatic rings from simple starting materials. The reaction proceeds modified Friedländer annulation and subsequent base-mediated benzannulation with acrylates as Michael acceptors.

Efficacy of Integrated Yoga and Ayurveda Rasayana on cognitive functions in elderly with mild cognitive impairment: Non-randomized three-arm clinical trial.

Background: Yoga and Ayurveda are ancient sciences which emphasize on the cure of disease and the proportion of health. Both sciences are also known to reduce the aging process and are helpful in aging-related disorders.

Objective: This study investigates the effects of Yoga and Ayurveda Rasayana combined intervention on cognition among the elderly with mild cognitive impairment.

Impact of Yoga on cognition and mental health among elderly: A systematic review.

Background: Cognitive decline and psychological health problems are the most frequently observed and under-treated issues among the elderly. Many studies have assessed the efficacy of Yoga on cognitive and mental health parameters among the elderly. However, up to date, there is no systematic review done to evaluate the role of Yoga-based interventions on cognition and mental health in the elderly.