Genome-Wide Characterization of the Heat Shock Transcription Factor Gene Family in Reveals Promising Candidates for Heat Tolerance.

Heat stress transcription factors (HSFs) play a critical role in orchestrating cellular responses to elevated temperatures and various stress conditions. While extensively studied in model plants, the gene family in remains unexplored, despite the availability of its sequenced genome. In this study, we employed bioinformatics approaches to identify 21 genes within the genome, revealing their uneven distribution across chromosomes.

SARS-CoV-2 spike host cell surface exposure promoted by a COPI sorting inhibitor.

an insufficient coat protein complex I (COPI) retrieval signal, the majority of SARS-CoV-2 spike (S) is resident in host early secretory organelles and a tiny amount is leaked out in cell surface. Only surface-exposed S can be recognized by B cell receptor (BCR) or anti-S therapeutic monoclonal antibodies (mAbs) that is the trigger step for B cell activation after S mRNA vaccination or infected cell clearance by S mAbs. Now, a drug strategy to promote S host surface exposure is absent.

Antioxidation and symbiotic nitrogen fixation function of prxA gene in Mesorhizobium huakuii.

Peroxiredoxins (Prxs) play an essential role in the antioxidant activity and symbiotic capacity of Mesorhizobium huakuii. A mutation in the M. huakuii prxA gene (encoding a Prx5-like peroxiredoxin) was generated by homologous recombination.