Publications by authors named "Sanjeev R Janarthanan"
Article Synopsis
- Some individuals react differently to chronic stress, with some being more susceptible while others display resilience.
- This study focuses on the lateral habenula (LHb), which is involved in signaling negative outcomes, to see how its activity differs between susceptible and resilient mice during stress.
- Findings reveal that susceptible mice exhibit increased LHb activity during stress, particularly when near aggressors, leading to long-lasting effects on brain activity and behavior that promote further susceptibility.
Animals learn the value of foods based on their postingestive effects and thereby develop aversions to foods that are toxic and preferences to those that are nutritious. However, it remains unclear how the brain is able to assign credit to flavors experienced during a meal with postingestive feedback signals that can arise after a substantial delay. Here, we reveal an unexpected role for postingestive reactivation of neural flavor representations in this temporal credit assignment process.
View Article and Find Full Text PDF