A Systematic Review of the Effectiveness of Bisphosphonates for Otosclerosis.

Objective: To systematically review the evidence for the use of bisphosphonate therapy in otosclerosis through clinically relevant outcomes.

Databases Reviewed: MEDLINE, EMBASE, PubMed, and CINAHL databases were searched up to July 12, 2021.

Methods: RCTs and cohort studies investigating the effect of bisphosphate therapy on adults or children diagnosed with otosclerosis were included.