Ruthenium complex based nanocomposite film with enhanced and selective electrochemical sensing of bifenthrin pesticide.

Bifenthrin (BF), a widely used pyrethroid pesticide in farming, lacks highly sensitive and selective sensors despite its extensive application. Ruthenium complexes are very effective for selective sensing applications but suffer from structural instability at elevated conditions, electrochemical activity, and the use of costly electrolytes. This work improves their electrochemical activity and mechanical strength by incorporating silver nanowires and replacing the costly electrolyte with abundant KCl + PBS, resulting in enhanced signal performance.

Highly selective and flexible silver nanoparticles-based paper sensor for on-site colorimetric detection of paraquat pesticide.

Paper-based sensors or paper-based analytical devices (PADs) have recently emerged as the cost-efficient, and portable, on-site detection tools for various biological and environmental analytes. However, paper-based sensors often suffer from poor selectivity. Here, a single-step paper-based flexible sensor platform has been developed for the on-site detection of paraquat (PQ) pesticide in real samples, utilizing chitosan and citrate-capped silver nanoparticles integrated with a flexible paper.

Severe dengue infection unmasking drug-induced liver injury: Successful management with N-acetylcysteine.

Key Clinical Message: Clinicians in tuberculosis and dengue endemic regions should have heightened vigilance for drug-induced liver injury (DILI) overlapping with active infections, enabling prompt recognition and life-saving conservative management.

Abstract: Severe dengue and drug-induced liver injury (DILI) are significant independent risk factors for acute liver failure. The co-occurrence of these conditions significantly complicates clinical management.

Paediatric Moyamoya disease: acute presentation with fever and confusion in an 8-year-old: a case report.

Introduction And Importance: Moyamoya is a chronic vaso-occlusive cerebrovascular disorder which involves internal carotid artery and its proximal branches, forming compensatory Moyamoya vessels. It may manifest with diverse symptoms, but early detection is crucial for a favourable prognosis.

Case Presentation: The authors present a case of an 8-year-old child who presented to the emergency with acute onset fever and confusion in speech.

Dermatomyositis with positive anti-TIF1 gamma antibodies in an adult female: A case report.

Dermatomyositis is an uncommon autoimmune disease with only few cases reported from Nepal. Presence of anti TIF-1 gamma antibodies in DM are the strongest predictor of malignancy. Timely screening of malignancies for early detection and management remains the mainstay of this report.

Bronchopleural fistula associated persistent pneumothorax in a patient recovering from COVID-19 pneumonia: A case report.

Key Clinical Message: Pneumothorax and bronchopleural fistula (BPF) are potentially fatal complications that can occur in patients with COVID-19 pneumonia. Early detection, appropriate treatment, and consideration of surgical intervention are necessary for optimum outcomes.

Introduction: Healthcare professionals face complex challenges as a result of the rare emergence of pneumothorax among the variety of COVID-19 complications, including severe viral pneumonia.

Management of Diabetic Ketoacidosis in a Patient With Chronic Kidney Disease Under Maintenance Hemodialysis: A Case Report.

Diabetic ketoacidosis (DKA) is a potentially fatal metabolic complication seen in individuals with type 1 diabetes mellitus (DM) or type 2 DM under stress, such as infections and non-compliance with treatment. DKA in chronic kidney disease (CKD) patients undergoing maintenance hemodialysis (HD) presents challenges due to the unique pathophysiology and the absence of specific management guidelines. This case report highlights the importance of tailoring the treatment of DKA based on the specific requirements of CKD patients on HD.