Publications by authors named "Sanjeet Kumar Mahtha"

teroidogenic cute egulatory rotein ()-elated ipid ransfer (START) domain represents an evolutionarily conserved superfamily of widely distributed across the tree of life. Despite significant expansion in plants, knowledge about this domain remains inadequate in plants. In this work, we explore the role of cavity architectural modulations in START protein evolution and functional diversity.

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Global warming exhibits profound effects on plant fitness and productivity. To withstand stress, plants sacrifice their growth and activate protective stress responses for ensuring survival. However, the switch between growth and stress is largely elusive.

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Article Synopsis
  • START proteins are essential for lipid transport, signaling, and transcription modulation in plants, with a focus on their evolution and functional roles in rice.
  • A study of 10 rice varieties shows that START domains are highly conserved, indicating their critical importance in plant functions and strong evolutionary pressures.
  • The research highlights sub-functionalization among START genes related to different developmental stages, suggesting that understanding these proteins could enhance our knowledge of plant biology compared to existing studies in animals and yeast.
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Plant genomes can withstand small- and large-scale duplications, at a far greater success than any other kingdom in the tree of life, resulting in the existence and evolution of gene families, often with over a hundred members! The gene families, in turn, go through subfunctionalization or neofunctionalization, to form protein domains performing unique or grouped functions in context of the original activity. Due to the large number of such cases in the plant kingdom, it has become a routine task for plant biologists to investigate their specific gene family of interest. In this chapter, we provide a simple and standard pipeline for this effort, taking the example of steroidogenic acute regulatory protein (StAR) related lipid transfer (START) domains in rice, as reference.

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Abiotic stress tolerance is a complex trait regulated by multiple genes and gene networks in plants. A range of abiotic stresses are known to limit rice productivity. Meta-transcriptomics has emerged as a powerful approach to decipher stress-associated molecular network in model crops.

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